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Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile rats

Objective: The aim of this study was to compare the pharmacokinetics and steady-state serum concentrations of lenvatinib in adult and juvenile rats. Experimental study: An ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method was developed to quantify lenvatinib in the serum and...

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Detalles Bibliográficos
Autores principales:	Du, Xiaoyue, Cai, Hongxin, Jin, Nan, Wu, Zhiguo, Wang, Lele, Wang, Zeyu, Xie, Baogang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420079/ https://www.ncbi.nlm.nih.gov/pubmed/37576809 http://dx.doi.org/10.3389/fphar.2023.1140849

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