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Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study

Scientific literature suggests that pregnant women are at greater risk of acquiring a more severe form of COVID-19 exposing both mother and child to a higher risk of obstetric and neonatal complications. These include increased hospitalization rates, ICU admissions, or ventilatory support among preg...

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Autores principales: Zehra, Syeda Mahjabeen, Parkar, Sadia, Kazi, Zaubina, Pethani, Asma, Malik, Ayesha, Mirza, Adnan, Abro, Falak, Jabbar, Hassan Abdul, Saleem, Ali Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420353/
https://www.ncbi.nlm.nih.gov/pubmed/37566567
http://dx.doi.org/10.1371/journal.pgph.0002139
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author Zehra, Syeda Mahjabeen
Parkar, Sadia
Kazi, Zaubina
Pethani, Asma
Malik, Ayesha
Mirza, Adnan
Abro, Falak
Jabbar, Hassan Abdul
Saleem, Ali Faisal
author_facet Zehra, Syeda Mahjabeen
Parkar, Sadia
Kazi, Zaubina
Pethani, Asma
Malik, Ayesha
Mirza, Adnan
Abro, Falak
Jabbar, Hassan Abdul
Saleem, Ali Faisal
author_sort Zehra, Syeda Mahjabeen
collection PubMed
description Scientific literature suggests that pregnant women are at greater risk of acquiring a more severe form of COVID-19 exposing both mother and child to a higher risk of obstetric and neonatal complications. These include increased hospitalization rates, ICU admissions, or ventilatory support among pregnant women when compared to COVID-19 negative pregnant womenA case-control study was conducted at the Aga Khan University Hospital, Karachi, Pakistan with the objective of evaluating the clinical presentation of COVID-19 in pregnancy and its effect on maternal and neonatal outcomes. Data was retrospectively collected from April 2020 till January 2022 of obstetric patients with COVID-19 positive cases and were compared with COVID-19 negative cases from the same time. A total of 491 women were included in the study, 244 cases and 247 controls. The most common complication amongst cases was gestational diabetes mellitus (n = 59, 24%), followed by gestational hypertension (n = 16, 31.7%), pre-eclampsia (n = 13, 5%) Pre-rupture of membrane (85.7%). Amongst the COVID positive mothers the most common presenting complaints were fever followed by dry cough, headache, and shortness of breath. It was observed that COVID-19 did not result in increased adverse maternal or neonatal outcomes compared to COVID-19 negative mothers.
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spelling pubmed-104203532023-08-12 Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study Zehra, Syeda Mahjabeen Parkar, Sadia Kazi, Zaubina Pethani, Asma Malik, Ayesha Mirza, Adnan Abro, Falak Jabbar, Hassan Abdul Saleem, Ali Faisal PLOS Glob Public Health Research Article Scientific literature suggests that pregnant women are at greater risk of acquiring a more severe form of COVID-19 exposing both mother and child to a higher risk of obstetric and neonatal complications. These include increased hospitalization rates, ICU admissions, or ventilatory support among pregnant women when compared to COVID-19 negative pregnant womenA case-control study was conducted at the Aga Khan University Hospital, Karachi, Pakistan with the objective of evaluating the clinical presentation of COVID-19 in pregnancy and its effect on maternal and neonatal outcomes. Data was retrospectively collected from April 2020 till January 2022 of obstetric patients with COVID-19 positive cases and were compared with COVID-19 negative cases from the same time. A total of 491 women were included in the study, 244 cases and 247 controls. The most common complication amongst cases was gestational diabetes mellitus (n = 59, 24%), followed by gestational hypertension (n = 16, 31.7%), pre-eclampsia (n = 13, 5%) Pre-rupture of membrane (85.7%). Amongst the COVID positive mothers the most common presenting complaints were fever followed by dry cough, headache, and shortness of breath. It was observed that COVID-19 did not result in increased adverse maternal or neonatal outcomes compared to COVID-19 negative mothers. Public Library of Science 2023-08-11 /pmc/articles/PMC10420353/ /pubmed/37566567 http://dx.doi.org/10.1371/journal.pgph.0002139 Text en © 2023 Zehra et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zehra, Syeda Mahjabeen
Parkar, Sadia
Kazi, Zaubina
Pethani, Asma
Malik, Ayesha
Mirza, Adnan
Abro, Falak
Jabbar, Hassan Abdul
Saleem, Ali Faisal
Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title_full Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title_fullStr Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title_full_unstemmed Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title_short Impact of COVID-19 on feto-maternal and neonatal health in Karachi, Pakistan, A retrospective cohort study
title_sort impact of covid-19 on feto-maternal and neonatal health in karachi, pakistan, a retrospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420353/
https://www.ncbi.nlm.nih.gov/pubmed/37566567
http://dx.doi.org/10.1371/journal.pgph.0002139
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