Comparative Molecular Characterization and Pharmacokinetics of IgG1-Fc and Engineered Fc Human Antibody Variants to Insulin-like Growth Factor 2 Receptor (IGF2R)

Novel therapeutic approaches are much needed for the treatment of osteosarcoma. Targeted radionuclide therapy (TRT) and radioimmunotherapy (RIT) are promising approaches that deliver therapeutic radiation precisely to the tumor site. We have previously developed a fully human antibody, named IF3, th...

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Detalles Bibliográficos
Autores principales: Prabaharan, Chandra B., Giri, Sabeena, Allen, Kevin J. H., Bato, Katrina E. M., Mercado, Therese R., Malo, Mackenzie E., Carvalho, Jorge L. C., Dadachova, Ekaterina, Uppalapati, Maruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420659/
https://www.ncbi.nlm.nih.gov/pubmed/37570809
http://dx.doi.org/10.3390/molecules28155839

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