Temporal scaling of dopamine neuron firing and dopamine release by distinct ion channels shape behavior

Dopamine is broadly implicated in reinforcement learning, but how patterns of dopamine activity are generated is poorly resolved. Here, we demonstrate that two ion channels, Kv4.3 and BKCa1.1, regulate the pattern of dopamine neuron firing and dopamine release on different time scales to influence s...

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Detalles Bibliográficos
Autores principales: Juarez, Barbara, Kong, Mi-Seon, Jo, Yong S., Elum, Jordan E., Yee, Joshua X., Ng-Evans, Scott, Cline, Marcella, Hunker, Avery C., Quinlan, Meagan A., Baird, Madison A., Elerding, Abigail J., Johnson, Mia, Ban, Derek, Mendez, Adriana, Goodwin, Nastacia L., Soden, Marta E., Zweifel, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421029/
https://www.ncbi.nlm.nih.gov/pubmed/37566654
http://dx.doi.org/10.1126/sciadv.adg8869

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