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A secreted sirtuin from Campylobacter jejuni contributes to neutrophil activation and intestinal inflammation during infection

Histone modifications control numerous processes in eukaryotes, including inflammation. Some bacterial pathogens alter the activity or expression of host-derived factors, including sirtuins, to modify histones and induce responses that promote infection. In this study, we identified a deacetylase en...

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Detalles Bibliográficos
Autores principales: Callahan, Sean M., Hancock, Trevor J., Doster, Ryan S., Parker, Caroline B., Wakim, Mary E., Gaddy, Jennifer A., Johnson, Jeremiah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421069/
https://www.ncbi.nlm.nih.gov/pubmed/37566649
http://dx.doi.org/10.1126/sciadv.ade2693