Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid

Docosahexaenoic acid (C22:6n-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families which have been considered therapeutic bioactive compounds for human health. Growing evidence indicates that DHA and SPMs are beneficial strate...

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Autores principales: Beyer, María Paz, Videla, Luis A., Farías, Camila, Valenzuela, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421104/
https://www.ncbi.nlm.nih.gov/pubmed/37571256
http://dx.doi.org/10.3390/nu15153317
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author Beyer, María Paz
Videla, Luis A.
Farías, Camila
Valenzuela, Rodrigo
author_facet Beyer, María Paz
Videla, Luis A.
Farías, Camila
Valenzuela, Rodrigo
author_sort Beyer, María Paz
collection PubMed
description Docosahexaenoic acid (C22:6n-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families which have been considered therapeutic bioactive compounds for human health. Growing evidence indicates that DHA and SPMs are beneficial strategies in the amelioration, regulation, and duration of inflammatory processes through different biological actions. The present review discusses the reported therapeutic benefits of SPMs on various diseases and their potential clinical applications.
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spelling pubmed-104211042023-08-12 Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid Beyer, María Paz Videla, Luis A. Farías, Camila Valenzuela, Rodrigo Nutrients Review Docosahexaenoic acid (C22:6n-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families which have been considered therapeutic bioactive compounds for human health. Growing evidence indicates that DHA and SPMs are beneficial strategies in the amelioration, regulation, and duration of inflammatory processes through different biological actions. The present review discusses the reported therapeutic benefits of SPMs on various diseases and their potential clinical applications. MDPI 2023-07-26 /pmc/articles/PMC10421104/ /pubmed/37571256 http://dx.doi.org/10.3390/nu15153317 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Beyer, María Paz
Videla, Luis A.
Farías, Camila
Valenzuela, Rodrigo
Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title_full Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title_fullStr Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title_full_unstemmed Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title_short Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
title_sort potential clinical applications of pro-resolving lipids mediators from docosahexaenoic acid
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421104/
https://www.ncbi.nlm.nih.gov/pubmed/37571256
http://dx.doi.org/10.3390/nu15153317
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