Cargando…

Supplementation of Dihomo-γ-Linolenic Acid for Pollen-Induced Allergic Symptoms in Healthy Subjects: A Randomized, Double-Blinded, Placebo-Controlled Trial

Dihomo-γ-linolenic acid (DGLA) is an n-6 polyunsaturated fatty acid that has been shown to have anti-inflammatory and anti-allergic effects in mice and cell study. To date, however, no human intervention study has examined the effects of DGLA. Therefore, we investigated the effects of DGLA on pollen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yokoi, Kaori, Yanagimoto, Kenichi, Hayamizu, Kohsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421109/ https://www.ncbi.nlm.nih.gov/pubmed/37571402 http://dx.doi.org/10.3390/nu15153465

Ejemplares similares

Effect of Docosahexaenoic Acid and Eicosapentaenoic Acid Supplementation on Sleep Quality in Healthy Subjects: A Randomized, Double-Blinded, Placebo-Controlled Trial
por: Yokoi-Shimizu, Kaori, et al.
Publicado: (2022)

Multiple roles of dihomo-γ-linolenic acid against proliferation diseases
por: Wang, Xiaoping, et al.
Publicado: (2012)

Dihydroxy-Metabolites of Dihomo-γ-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration
por: Sarparast, Morteza, et al.
Publicado: (2023)

Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis
por: Gallagher, Hayley, et al.
Publicado: (2019)

Eicosapentaenoic and docosahexaenoic acids-rich fish oil supplementation attenuates strength loss and limited joint range of motion after eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial
por: Tsuchiya, Yosuke, et al.
Publicado: (2016)

The Linoleic Acid: Dihomo-γ-Linolenic Acid Ratio (LA:DGLA)—An Emerging Biomarker of Zn Status
por: Knez, Marija, et al.
Publicado: (2017)

Palmitoleic and Dihomo-γ-Linolenic Acids Are Positively Associated With Abdominal Obesity and Increased Metabolic Risk in Children
por: Hua, Man-Chin, et al.
Publicado: (2021)

Physiological Traits of Dihomo-γ-Linolenic Acid Production of the Engineered Aspergillus oryzae by Comparing Mathematical Models
por: Antimanon, Sompot, et al.
Publicado: (2020)

Dihomo-γ-Linolenic Acid (20:3n-6)—Metabolism, Derivatives, and Potential Significance in Chronic Inflammation
por: Mustonen, Anne-Mari, et al.
Publicado: (2023)

Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo-γ-linolenic acid for colon cancer suppression
por: Xu, Yi, et al.
Publicado: (2018)

Dihydroxy-Metabolites of Dihomo-gamma-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration
por: Sarparast, Morteza, et al.
Publicado: (2023)

Dietary patterns related to zinc and polyunsaturated fatty acids intake are associated with serum linoleic/dihomo-γ-linolenic ratio in NHANES males and females
por: Monteiro, Jacqueline Pontes, et al.
Publicado: (2021)

Increased Serum Dihomo-γ-linolenic Acid Levels Are Associated with Obesity, Body Fat Accumulation, and Insulin Resistance in Japanese Patients with Type 2 Diabetes
por: Tsurutani, Yuya, et al.
Publicado: (2018)

Epoxides Derived from Dietary Dihomo-Gamma-Linolenic Acid Induce Germ Cell Death in C. elegans
por: Deline, Marshall, et al.
Publicado: (2015)

Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase
por: Xu, Yi, et al.
Publicado: (2018)

Serum Levels of Dihomo-Gamma (γ)-Linolenic Acid (DGLA) Are Inversely Associated with Linoleic Acid and Total Death in Elderly Patients with a Recent Myocardial Infarction
por: Nilsen, Dennis Winston T., et al.
Publicado: (2021)

Free radical derivatives formed from cyclooxygenase-catalyzed dihomo-γ-linolenic acid peroxidation can attenuate colon cancer cell growth and enhance 5-fluorouracil׳s cytotoxicity
por: Xu, Yi, et al.
Publicado: (2014)

Dietary Zinc Deficiency Affects Blood Linoleic Acid: Dihomo-γ-linolenic Acid (LA:DGLA) Ratio; a Sensitive Physiological Marker of Zinc Status in Vivo (Gallus gallus)
por: Reed, Spenser, et al.
Publicado: (2014)

Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA
por: Yang, Xiaoyu, et al.
Publicado: (2018)

Decreased circulating dihomo-gamma-linolenic acid levels are associated with total mortality in patients with acute cardiovascular disease and acute decompensated heart failure
por: Ouchi, Shohei, et al.
Publicado: (2017)

Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism
por: Xu, Yi, et al.
Publicado: (2018)

Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers
por: Konagai, Chizuru, et al.
Publicado: (2013)

Low Docosahexaenoic Acid, Dihomo-Gamma-Linolenic Acid, and Arachidonic Acid Levels Associated with Long-Term Mortality in Patients with Acute Decompensated Heart Failure in Different Nutritional Statuses
por: Ouchi, Shohei, et al.
Publicado: (2017)

The effect of alpha-linolenic acid supplementation on ADHD symptoms in children: a randomized controlled double-blind study
por: Dubnov-Raz, Gal, et al.
Publicado: (2014)

ω-3 fatty acids, γ-linolenic acid, and antioxidants: immunomodulators or inert dietary supplements?
por: Schott, Christopher K, et al.
Publicado: (2012)

Intralymphatic immunotherapy of pollen-induced rhinoconjunctivitis: a double-blind placebo-controlled trial
por: Hylander, Terese, et al.
Publicado: (2016)

Effect of γ-tocopherol supplementation on premenstrual symptoms and natriuresis: a randomized, double-blind, placebo-controlled study
por: Higuchi, Tomoko, et al.
Publicado: (2023)

A Change-Point Regression Approach for Efficacy Evaluation of Dietary Supplements
por: Hayamizu, Kohsuke, et al.
Publicado: (2009)

Influence of Ingestion of Eicosapentaenoic Acid-Rich Fish Oil on Oxidative Stress at the Menstrual Phase: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial
por: Mano, Yoshihiko, et al.
Publicado: (2022)

Pollen allergic disease: pollens and its major allergens
por: Taketomi, Ernesto Akio, et al.
Publicado: (2015)

γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial
por: Won, Jong Chul, et al.
Publicado: (2020)

Does pomegranate extract supplementation improve the clinical symptoms of patients with allergic asthma? A double-blind, randomized, placebo-controlled trial
por: Hosseini, Seyed Ahmad, et al.
Publicado: (2023)

Aeration effect on Spirulina platensis growth and γ-Linolenic acid production
por: Ronda, Srinivasa Reddy, et al.
Publicado: (2012)

n-3 fatty acids, γ-linolenic acid, and antioxidants in sepsis
por: Das, Undurti N
Publicado: (2013)

Economic Evaluation of 5-Grass Pollen Tablets Versus Placebo in the Treatment of Allergic Rhinitis in Adults
por: Ruggeri, Matteo, et al.
Publicado: (2013)

Culture Conditions stimulating high γ-Linolenic Acid accumulation by Spirulina platensis
por: Ronda, Srinivasa Reddy, et al.
Publicado: (2008)

Glucosamine-containing supplement improves locomotor functions in subjects with knee pain: a randomized, double-blind, placebo-controlled study
por: Kanzaki, Noriyuki, et al.
Publicado: (2015)

Oral administration of Lactobacillus paracasei NCC 2461 for the modulation of grass pollen allergic rhinitis: a randomized, placebo-controlled study during the pollen season
por: Nembrini, Chiara, et al.
Publicado: (2015)

29 Allergic Rhinitis to Ragweed Pollen
por: Bocsan, Ioana Corina, et al.
Publicado: (2012)

Clinical and immunological effects of vitamin D supplementation during the pollen season in children with allergic rhinitis
por: Jerzyńska, Joanna, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h9tunp45o0l4d8i9ljkmv60lf2