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Redox Regulation in Age-Related Cataracts: Roles for Glutathione, Vitamin C, and the NRF2 Signaling Pathway

Age is the biggest risk factor for cataracts, and aberrant oxidative modifications are correlated with age-related cataracts, suggesting that proper redox regulation is important for lens clarity. The lens has very high levels of antioxidants, including ascorbate and glutathione that aid in keeping...

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Detalles Bibliográficos
Autores principales: Bejarano, Eloy, Weinberg, Jasper, Clark, Madison, Taylor, Allen, Rowan, Sheldon, Whitcomb, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421530/
https://www.ncbi.nlm.nih.gov/pubmed/37571310
http://dx.doi.org/10.3390/nu15153375