Investigating the composition and recruitment of the mycobacterial ImuA′–ImuB–DnaE2 mutasome

A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence of drug resistance in Mycobacterium tuberculosis during anti-tuberculosis (TB) chemotherapy. However, the molecular composition and operation of the encoded ‘mycobacterial mutasome’ – minimally comprising DnaE2 polym...

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Detalles Bibliográficos
Autores principales: Gessner, Sophia, Martin, Zela Alexandria-Mae, Reiche, Michael A, Santos, Joana A, Dinkele, Ryan, Ramudzuli, Atondaho, Dhar, Neeraj, de Wet, Timothy J, Anoosheh, Saber, Lang, Dirk M, Aaron, Jesse, Chew, Teng-Leong, Herrmann, Jennifer, Müller, Rolf, McKinney, John D, Woodgate, Roger, Mizrahi, Valerie, Venclovas, Česlovas, Lamers, Meindert H, Warner, Digby F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421592/
https://www.ncbi.nlm.nih.gov/pubmed/37530405
http://dx.doi.org/10.7554/eLife.75628

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