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Cytosolic DNA sensing protein pathway is activated in human hearts with dilated cardiomyopathy
INTRODUCTION: The genome is constantly exposed to numerous stressors, which induce DNA lesions, including double-stranded DNA breaks (DSBs). DSBs are the most dangerous, as they induce genomic instability. In response to DNA damage, the cell activates nuclear DNA damage response (DDR) and the cytoso...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421632/ https://www.ncbi.nlm.nih.gov/pubmed/37577061 http://dx.doi.org/10.20517/jca.2023.20 |