MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation

Heart failure is a major side effect of doxorubicin (DOX) treatment in patients with cancer. However, the mechanisms underlying the development of DOX-induced heart failure need to be addressed. This study aims to test whether the serine/threonine kinase MST1, a major Hippo pathway component, contri...

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Detalles Bibliográficos
Autores principales: Schirone, Leonardo, Vecchio, Daniele, Valenti, Valentina, Forte, Maurizio, Relucenti, Michela, Angelini, Annalisa, Zaglia, Tania, Schiavon, Sonia, D’Ambrosio, Luca, Sarto, Gianmarco, Stanzione, Rosita, Mangione, Elisa, Miglietta, Selenia, Di Bona, Anna, Fedrigo, Marny, Ghigo, Alessandra, Versaci, Francesco, Petrozza, Vincenzo, Marchitti, Simona, Rubattu, Speranza, Volpe, Massimo, Sadoshima, Junichi, Frati, Luigi, Frati, Giacomo, Sciarretta, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421787/
https://www.ncbi.nlm.nih.gov/pubmed/37566283
http://dx.doi.org/10.1007/s00018-023-04877-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421787/
https://www.ncbi.nlm.nih.gov/pubmed/37566283
http://dx.doi.org/10.1007/s00018-023-04877-7

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