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Thermoresponsive Gel-loaded Oxcarbazepine Nanosystems for Nose- To-Brain Delivery: Enhanced Antiepileptic Activity in Rats

BACKGROUND: Oxcarbazepine (OXC) is a frequently prescribed antiepileptic drug for managing focal and generalized seizures. Its therapeutic benefits are limited by its dose-dependent side effects. Nose-to-brain delivery is a novel route for improving the efficacy of antiepileptics. Drug encapsulation...

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Detalles Bibliográficos
Autores principales:	Abou-Taleb, Basant A., El-Ganainy, Samar O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421799/ https://www.ncbi.nlm.nih.gov/pubmed/37353628 http://dx.doi.org/10.1007/s11095-023-03552-7

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