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Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies

Aberrantly expressed onco-mucin 16 (MUC16) and its post-cleavage generated surface tethered carboxy-terminal (MUC16-Cter) domain are strongly associated with poor prognosis and lethality of pancreatic (PC) and non-small cell lung cancer (NSCLC). To date, most anti-MUC16 antibodies are directed towar...

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Detalles Bibliográficos
Autores principales:	Shah, Ashu, Chaudhary, Sanjib, Lakshmanan, Imayavaramban, Aithal, Abhijit, Kisling, Sophia G., Sorrell, Claire, Marimuthu, Saravanakumar, Gautam, Shailendra K., Rauth, Sanchita, Kshirsagar, Prakash, Cox, Jesse L., Natarajan, Gopalakrishnan, Bhatia, Rakesh, Mallya, Kavita, Rachagani, Satyanarayana, Nasser, Mohd Wasim, Ganti, Apar Kishor, Salgia, Ravi, Kumar, Sushil, Jain, Maneesh, Ponnusamy, Moorthy P., Batra, Surinder K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421872/ https://www.ncbi.nlm.nih.gov/pubmed/37567918 http://dx.doi.org/10.1038/s41698-023-00423-7

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