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Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells

The prognosis of high-grade gliomas, such as glioblastoma multiforme (GBM), is extremely poor due to the highly invasive nature of these aggressive cancers. Previous work has demonstrated that TNF-weak like factor (TWEAK) induction of the noncanonical NF-κB pathway promotes the invasiveness of GBM c...

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Detalles Bibliográficos
Autores principales: Pflug, Kathryn M., Lee, Dong W., McFadden, Kassandra, Herrera, Linda, Sitcheran, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421885/
https://www.ncbi.nlm.nih.gov/pubmed/37567906
http://dx.doi.org/10.1038/s41598-023-38996-9