Cargando…

A tailored phase I-specific patient-reported outcome (PRO) survey to capture the patient experience of symptomatic adverse events

BACKGROUND: Patient perspectives are fundamental to defining tolerability of investigational anti-neoplastic therapies in clinical trials. Phase I trials present a unique challenge in designing tools for efficiently collecting patient-reported outcomes (PROs) given the difficulty of anticipating adv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janse van Rensburg, Helena J., Liu, Zhihui, Watson, Geoffrey A., Veitch, Zachary W., Shepshelovich, Daniel, Spreafico, Anna, Abdul Razak, Albiruni R., Bedard, Philippe L., Siu, Lillian L., Minasian, Lori, Hansen, Aaron R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421959/ https://www.ncbi.nlm.nih.gov/pubmed/37419999 http://dx.doi.org/10.1038/s41416-023-02307-w

Ejemplares similares

Longitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy
por: Spiliopoulou, Pavlina, et al.
Publicado: (2023)

Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry
por: Music, Milena, et al.
Publicado: (2020)

Survival in Early Phase Immuno-Oncology Trials: Development and Validation of a Prognostic Index
por: Day, Daphne, et al.
Publicado: (2019)

Predicting Toxicity and Response to Pembrolizumab Through Germline Genomic HLA Class 1 Analysis
por: Iafolla, Marco A J, et al.
Publicado: (2020)

Circulating Biomarkers for Therapeutic Monitoring of Anti-cancer Agents
por: Janse van Rensburg, Helena J, et al.
Publicado: (2022)

Clinician and Patient Reporting of Symptomatic Adverse Events in Cancer Clinical Trials: Using CTCAE and PRO-CTCAE(®) to Provide Two Distinct and Complementary Perspectives
por: Minasian, Lori M, et al.
Publicado: (2022)

Cancer patients’ experiences with immune checkpoint modulators: A qualitative study
por: Ala‐Leppilampi, Kari, et al.
Publicado: (2020)

Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab
por: Watson, Geoffrey Alan, et al.
Publicado: (2022)

Applications of Circulating Tumor DNA in a Cohort of Phase I Solid Tumor Patients Treated With Immunotherapy
por: Araujo, Daniel V, et al.
Publicado: (2021)

Diagnostic accuracy and reliability of smartphone captured radiologic images communicated via WhatsApp®
por: Ntja, Unathi, et al.
Publicado: (2022)

Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)
por: Genta, Sofia, et al.
Publicado: (2023)

Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction
por: Voon, Pei Jye, et al.
Publicado: (2022)

Tailoring diagnosis and treatment in symptomatic gallstone disease
por: Latenstein, Carmen S S, et al.
Publicado: (2022)

Increasing operational and scientific efficiency in clinical trials
por: Kelly, Deirdre, et al.
Publicado: (2020)

A242 DELAYED STEROID TAPER MAY REDUCE RISK OF RELAPSE IN PATIENTS WITH IMMUNE CHECKPOINT INHIBITOR ASSOCIATED HEPATOTOXICIT
por: Almousawi, F, et al.
Publicado: (2023)

Clinical outcomes of non‐osteogenic, non‐Ewing soft‐tissue sarcoma of bone––experience of the Toronto Sarcoma Program
por: Veitch, Zachary W., et al.
Publicado: (2020)

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors
por: Taylor, Kirsty, et al.
Publicado: (2020)

A phase II study of ENMD-2076 in advanced soft tissue sarcoma (STS)
por: Veitch, Zachary, et al.
Publicado: (2019)

Evaluation of liver enzyme elevations and hepatotoxicity in patients treated with checkpoint inhibitor immunotherapy
por: Cunningham, Morven, et al.
Publicado: (2021)

Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications
por: Coppock, Matthew B., et al.
Publicado: (2017)

Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer
por: Pezo, Rossanna C., et al.
Publicado: (2017)

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors
por: Diaz-Padilla, Ivan, et al.
Publicado: (2013)

A Need for Tailored Approach for Patients with Symptomatic Intracranial Atherosclerotic Stenosis
por: Kate, Mahesh P., et al.
Publicado: (2020)

Reconciliation and psychiatry in South Africa
por: van Rensburg, Bernard Janse
Publicado: (2015)

Levels of health literacy and English comprehension in patients presenting to South African primary healthcare facilities
por: van Rensburg, Zelda Janse
Publicado: (2020)

COVID19, the pandemic which may exemplify a need for harm-reduction approaches to eating disorders: a reflection from a person living with an eating disorder
por: Janse van Rensburg, Margaret
Publicado: (2020)

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575)
por: Richter, Suzanne, et al.
Publicado: (2013)

Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
por: Cindy Yang, S. Y., et al.
Publicado: (2021)

Efficiency of New Dose Escalation Designs in Dose-Finding Phase I Trials of Molecularly Targeted Agents
por: Le Tourneau, Christophe, et al.
Publicado: (2012)

Transformative eating disorder research: qualitative research considerations
por: Janse van Rensburg, Margaret G.
Publicado: (2021)

Post-mortem evidence of a diverse distribution pattern of atherosclerosis in the South African population
por: van Rensburg, Walter J. Janse
Publicado: (2022)

Inpatient management of borderline personality disorder at Helen Joseph Hospital, Johannesburg
por: Paruk, Laila, et al.
Publicado: (2016)

Exogenous capture accounts for fundamental differences between pro- and antisaccade performance
por: Goldstein, Allison T, et al.
Publicado: (2022)

A dynamic version of the FRAM for capturing variability in complex operations
por: Salehi, Vahid, et al.
Publicado: (2021)

Medically tailored meals for the management of symptomatic ascites: the SALTYFOOD pilot randomized clinical trial
por: Tapper, Elliot B, et al.
Publicado: (2020)

Mean field analysis of algorithms for scale-free networks in molecular biology
por: Konini, S., et al.
Publicado: (2017)

Health policy and integrated mental health care in the SADC region: strategic clarification using the Rainbow Model
por: van Rensburg, André Janse, et al.
Publicado: (2016)

Fatty meal sonography comparing coconut oil and chocolate bar with full-fat yoghurt as cholecystagogues for gallbladder ejection fractions
por: Spangenberg, Benjamin, et al.
Publicado: (2018)

Advances in Precision Medicine: Tailoring Individualized Therapies
por: Matchett, Kyle B., et al.
Publicado: (2017)

Testing ERBB2 p.L755S kinase domain mutation as a druggable target in a patient with advanced colorectal cancer
por: Aung, Kyaw L., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dousmpintskgk5ttj2ot4rt97b