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IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation

We have demonstrated that oligodeoxynucleotide IMT504 promotes significant improvement in the diabetic condition in diverse animal models. Based on these results, here we evaluated whether these effects observed in vivo could be due to direct effects on β‐cells. We demonstrate by immunofluorescence...

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Detalles Bibliográficos
Autores principales: Converti, Ayelén, Bianchi, María Silvia, Martinez, Mario D., Montaner, Alejandro D., Lux‐Lantos, Victoria, Bonaventura, María Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421975/
https://www.ncbi.nlm.nih.gov/pubmed/37568265
http://dx.doi.org/10.14814/phy2.15790