Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy

Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruct...

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Autores principales: Moroni, Francesco, Chaturvedi, Abhishek, Jafree, Ehsan, Gertz, Zachary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421979/
https://www.ncbi.nlm.nih.gov/pubmed/37348836
http://dx.doi.org/10.1016/j.ihj.2023.06.007
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author Moroni, Francesco
Chaturvedi, Abhishek
Jafree, Ehsan
Gertz, Zachary M.
author_facet Moroni, Francesco
Chaturvedi, Abhishek
Jafree, Ehsan
Gertz, Zachary M.
author_sort Moroni, Francesco
collection PubMed
description Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruction over time has never been described. We analyzed retrospectively 40 patients with HCM and no baseline obstruction followed up for a median of 2179 days. At follow up, 13 patients developed significant LVOTO. Patients who developed LVOTO had longer posterior leaflets and longer anterior leaflet residual length.
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spelling pubmed-104219792023-08-13 Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy Moroni, Francesco Chaturvedi, Abhishek Jafree, Ehsan Gertz, Zachary M. Indian Heart J Short Communication Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruction over time has never been described. We analyzed retrospectively 40 patients with HCM and no baseline obstruction followed up for a median of 2179 days. At follow up, 13 patients developed significant LVOTO. Patients who developed LVOTO had longer posterior leaflets and longer anterior leaflet residual length. Elsevier 2023 2023-06-20 /pmc/articles/PMC10421979/ /pubmed/37348836 http://dx.doi.org/10.1016/j.ihj.2023.06.007 Text en © 2023 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Moroni, Francesco
Chaturvedi, Abhishek
Jafree, Ehsan
Gertz, Zachary M.
Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title_full Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title_fullStr Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title_full_unstemmed Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title_short Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
title_sort mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421979/
https://www.ncbi.nlm.nih.gov/pubmed/37348836
http://dx.doi.org/10.1016/j.ihj.2023.06.007
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