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Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants
Abortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district J...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422025/ https://www.ncbi.nlm.nih.gov/pubmed/37576834 http://dx.doi.org/10.3389/fvets.2023.1195274 |
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author | Zeeshan, Muhammad Abid Ali, Sarmad Ahmed, Ishtiaq Rehman, Aziz ur Rafique, Muhammad Kamran Nasir, Amar Khan, Aman Ullah Kashif, Muhammad Mertens-Scholz, Katja Arshad, Muhammad Imran Ehtisham-ul-Haque, Syed Neubauer, Heinrich |
author_facet | Zeeshan, Muhammad Abid Ali, Sarmad Ahmed, Ishtiaq Rehman, Aziz ur Rafique, Muhammad Kamran Nasir, Amar Khan, Aman Ullah Kashif, Muhammad Mertens-Scholz, Katja Arshad, Muhammad Imran Ehtisham-ul-Haque, Syed Neubauer, Heinrich |
author_sort | Zeeshan, Muhammad Abid |
collection | PubMed |
description | Abortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district Jhang. A total of 385 serum samples were taken from the sheep and goats from different flocks with a history of abortion and subjected to i-ELISA. Further, samples were analysed for liver enzymes and total serum protein using a semi-automated chemistry analyzer. The result of indirect commercial ELISA showed 13.0, 4.2 and 11.2% prevalence for Coxiella burnetii, Chlamydia abortus, and Brucella spp., respectively. Values of different serum parameters (ALT, AST, and total protein) of seropositive animals were also determined. There was a significant rise in AST and ALT values of infected animals (p ≤ 0.05). Total protein decreased for all three infections, but a significant drop was noted in Brucella positive sheep serum samples. Various risk factors were studied. Binary logistic regression proved a significant role of ticks for coxiellosis and brucellosis. Age, parity, and species did not impact the prevalence of diseases studied. |
format | Online Article Text |
id | pubmed-10422025 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104220252023-08-13 Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants Zeeshan, Muhammad Abid Ali, Sarmad Ahmed, Ishtiaq Rehman, Aziz ur Rafique, Muhammad Kamran Nasir, Amar Khan, Aman Ullah Kashif, Muhammad Mertens-Scholz, Katja Arshad, Muhammad Imran Ehtisham-ul-Haque, Syed Neubauer, Heinrich Front Vet Sci Veterinary Science Abortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district Jhang. A total of 385 serum samples were taken from the sheep and goats from different flocks with a history of abortion and subjected to i-ELISA. Further, samples were analysed for liver enzymes and total serum protein using a semi-automated chemistry analyzer. The result of indirect commercial ELISA showed 13.0, 4.2 and 11.2% prevalence for Coxiella burnetii, Chlamydia abortus, and Brucella spp., respectively. Values of different serum parameters (ALT, AST, and total protein) of seropositive animals were also determined. There was a significant rise in AST and ALT values of infected animals (p ≤ 0.05). Total protein decreased for all three infections, but a significant drop was noted in Brucella positive sheep serum samples. Various risk factors were studied. Binary logistic regression proved a significant role of ticks for coxiellosis and brucellosis. Age, parity, and species did not impact the prevalence of diseases studied. Frontiers Media S.A. 2023-07-28 /pmc/articles/PMC10422025/ /pubmed/37576834 http://dx.doi.org/10.3389/fvets.2023.1195274 Text en Copyright © 2023 Zeeshan, Ali, Ahmed, Rehman, Rafique, Nasir, Khan, Kashif, Mertens-Scholz, Arshad, Ehtisham-ul-Haque and Neubauer. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Zeeshan, Muhammad Abid Ali, Sarmad Ahmed, Ishtiaq Rehman, Aziz ur Rafique, Muhammad Kamran Nasir, Amar Khan, Aman Ullah Kashif, Muhammad Mertens-Scholz, Katja Arshad, Muhammad Imran Ehtisham-ul-Haque, Syed Neubauer, Heinrich Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title_full | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title_fullStr | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title_full_unstemmed | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title_short | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
title_sort | sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422025/ https://www.ncbi.nlm.nih.gov/pubmed/37576834 http://dx.doi.org/10.3389/fvets.2023.1195274 |
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