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Interplay between Nrf2 and αB-crystallin in the lens and heart of zebrafish under proteostatic stress

A coordinated oxidative stress response, partly triggered by the transcription factor Nrf2, protects cells from the continual production of reactive oxygen species. Left unbuffered, reactive oxygen species can lead to protein aggregation that has been implicated in a spectrum of diseases such as cat...

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Detalles Bibliográficos
Autores principales: Park, Jinhee, MacGavin, Samantha, Niederbrach, Laurie, Mchaourab, Hassane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422029/
https://www.ncbi.nlm.nih.gov/pubmed/37577747
http://dx.doi.org/10.3389/fmolb.2023.1185704