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Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité

INTRODUCTION: pulmonary embolism is a real public health problem because of its high morbidity and mortality rate. The purpose of this study is to evaluate the impact of PESI score on the prognosis of pulmonary embolism. METHODS: we conducted a retrospective study of 146 cases of formally confirmed...

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Autores principales: Hassine, Majed, Kallala, Mohamed Yassine, Mahjoub, Marouen, Boussaada, Mehdi, Bouchahda, Nidhal, Gamra, Habib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422038/
https://www.ncbi.nlm.nih.gov/pubmed/37575526
http://dx.doi.org/10.11604/pamj.2023.45.48.39031
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author Hassine, Majed
Kallala, Mohamed Yassine
Mahjoub, Marouen
Boussaada, Mehdi
Bouchahda, Nidhal
Gamra, Habib
author_facet Hassine, Majed
Kallala, Mohamed Yassine
Mahjoub, Marouen
Boussaada, Mehdi
Bouchahda, Nidhal
Gamra, Habib
author_sort Hassine, Majed
collection PubMed
description INTRODUCTION: pulmonary embolism is a real public health problem because of its high morbidity and mortality rate. The purpose of this study is to evaluate the impact of PESI score on the prognosis of pulmonary embolism. METHODS: we conducted a retrospective study of 146 cases of formally confirmed embolism. Pulmonary embolism severity index (PESI) score was calculated for the entire study population. The patients were divided into 2 groups: a low-risk group (LR) comprising patients in risk classes I and II: 83 patients; a high-risk group (HR) comprising patients in risk classes III, IV and V: 63 patients; the primary endpoint of the study (MACE) was the occurrence of shock, the need for mechanical ventilation, and the occurrence of in-hospital death. RESULTS: total in-hospital mortality was 15.1%, significantly higher in the HR group (25.4% versus 7.2%, p=0.001). In logistic regression analysis, being in the HR group (OR=5.1; 95% CI: [1,637 - 16,093]; p=0.005)) and having renal impairment (OR=4.5; 95% CI: [1.457 – 14.075]; p=0.009) were the independent factors for the occurrence of MACE. After a mean follow-up of 18 ± 8 months, there were more deaths in the HR group (68.4% versus 33%, p=0.004). CONCLUSION: the results of our study show that the PESI score is correlated with the severity of PE. This should encourage the widespread use of this risk score.
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spelling pubmed-104220382023-08-13 Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité Hassine, Majed Kallala, Mohamed Yassine Mahjoub, Marouen Boussaada, Mehdi Bouchahda, Nidhal Gamra, Habib Pan Afr Med J Research INTRODUCTION: pulmonary embolism is a real public health problem because of its high morbidity and mortality rate. The purpose of this study is to evaluate the impact of PESI score on the prognosis of pulmonary embolism. METHODS: we conducted a retrospective study of 146 cases of formally confirmed embolism. Pulmonary embolism severity index (PESI) score was calculated for the entire study population. The patients were divided into 2 groups: a low-risk group (LR) comprising patients in risk classes I and II: 83 patients; a high-risk group (HR) comprising patients in risk classes III, IV and V: 63 patients; the primary endpoint of the study (MACE) was the occurrence of shock, the need for mechanical ventilation, and the occurrence of in-hospital death. RESULTS: total in-hospital mortality was 15.1%, significantly higher in the HR group (25.4% versus 7.2%, p=0.001). In logistic regression analysis, being in the HR group (OR=5.1; 95% CI: [1,637 - 16,093]; p=0.005)) and having renal impairment (OR=4.5; 95% CI: [1.457 – 14.075]; p=0.009) were the independent factors for the occurrence of MACE. After a mean follow-up of 18 ± 8 months, there were more deaths in the HR group (68.4% versus 33%, p=0.004). CONCLUSION: the results of our study show that the PESI score is correlated with the severity of PE. This should encourage the widespread use of this risk score. The African Field Epidemiology Network 2023-05-19 /pmc/articles/PMC10422038/ /pubmed/37575526 http://dx.doi.org/10.11604/pamj.2023.45.48.39031 Text en Copyright: Majed Hassine et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Hassine, Majed
Kallala, Mohamed Yassine
Mahjoub, Marouen
Boussaada, Mehdi
Bouchahda, Nidhal
Gamra, Habib
Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title_full Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title_fullStr Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title_full_unstemmed Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title_short Embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (ISEP) score et facteurs prédictifs de mortalité
title_sort embolie pulmonaire: indice de sévérité de l’embolie pulmonaire (isep) score et facteurs prédictifs de mortalité
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422038/
https://www.ncbi.nlm.nih.gov/pubmed/37575526
http://dx.doi.org/10.11604/pamj.2023.45.48.39031
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