The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer's disease

Based on single-cell sequencing of the hippocampi of 5× familiar Alzheimer's disease (5× FAD) and wild type mice at 2-, 12-, and 24-month of age, we found an increased percentage of microglia in aging and Alzheimer's disease (AD) mice. Blood brain barrier injury may also have contributed t...

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Detalles Bibliográficos
Autores principales: Li, He, Ye, Tianyuan, Liu, Xingyang, Guo, Rui, Yang, Xiuzhao, Li, Yangyi, Qi, Dongmei, Wei, Yihua, Zhu, Yifan, Wen, Lei, Cheng, Xiaorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422165/
https://www.ncbi.nlm.nih.gov/pubmed/37577391
http://dx.doi.org/10.1016/j.jpha.2023.05.008

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