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Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422303/ https://www.ncbi.nlm.nih.gov/pubmed/37571470 http://dx.doi.org/10.3390/s23156684 |
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author | Bello, Valentina Bodo, Elisabetta Merlo, Sabina |
author_facet | Bello, Valentina Bodo, Elisabetta Merlo, Sabina |
author_sort | Bello, Valentina |
collection | PubMed |
description | Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index and of the air bubble transit. The selected optofluidic platform has been designed and studied to be integrated into automatic pumps for the administration of commercial liquid. The sensor includes a laser beam that crosses twice a plastic cuvette, provided with a back mirror, and a position-sensitive detector. The identification of fluids is carried out by measuring the displacement of the output beam on the detector active surface and the detection of single air bubbles can be performed with the same instrumental scheme, exploiting a specific signal analysis. When a bubble, traveling along the cuvette, crosses the readout light beam, radiation is strongly scattered and a characteristic fingerprint shape of the photo-detected signals versus time is clearly observed. Experimental testing proves that air bubbles can be successfully detected and counted. Their traveling speed can be estimated while simultaneously monitoring the refractive index of the fluid. |
format | Online Article Text |
id | pubmed-10422303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104223032023-08-13 Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition Bello, Valentina Bodo, Elisabetta Merlo, Sabina Sensors (Basel) Article Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index and of the air bubble transit. The selected optofluidic platform has been designed and studied to be integrated into automatic pumps for the administration of commercial liquid. The sensor includes a laser beam that crosses twice a plastic cuvette, provided with a back mirror, and a position-sensitive detector. The identification of fluids is carried out by measuring the displacement of the output beam on the detector active surface and the detection of single air bubbles can be performed with the same instrumental scheme, exploiting a specific signal analysis. When a bubble, traveling along the cuvette, crosses the readout light beam, radiation is strongly scattered and a characteristic fingerprint shape of the photo-detected signals versus time is clearly observed. Experimental testing proves that air bubbles can be successfully detected and counted. Their traveling speed can be estimated while simultaneously monitoring the refractive index of the fluid. MDPI 2023-07-26 /pmc/articles/PMC10422303/ /pubmed/37571470 http://dx.doi.org/10.3390/s23156684 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bello, Valentina Bodo, Elisabetta Merlo, Sabina Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title | Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title_full | Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title_fullStr | Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title_full_unstemmed | Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title_short | Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition |
title_sort | optical multi-parameter measuring system for fluid and air bubble recognition |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422303/ https://www.ncbi.nlm.nih.gov/pubmed/37571470 http://dx.doi.org/10.3390/s23156684 |
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