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Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition

Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index a...

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Detalles Bibliográficos
Autores principales: Bello, Valentina, Bodo, Elisabetta, Merlo, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422303/
https://www.ncbi.nlm.nih.gov/pubmed/37571470
http://dx.doi.org/10.3390/s23156684
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author Bello, Valentina
Bodo, Elisabetta
Merlo, Sabina
author_facet Bello, Valentina
Bodo, Elisabetta
Merlo, Sabina
author_sort Bello, Valentina
collection PubMed
description Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index and of the air bubble transit. The selected optofluidic platform has been designed and studied to be integrated into automatic pumps for the administration of commercial liquid. The sensor includes a laser beam that crosses twice a plastic cuvette, provided with a back mirror, and a position-sensitive detector. The identification of fluids is carried out by measuring the displacement of the output beam on the detector active surface and the detection of single air bubbles can be performed with the same instrumental scheme, exploiting a specific signal analysis. When a bubble, traveling along the cuvette, crosses the readout light beam, radiation is strongly scattered and a characteristic fingerprint shape of the photo-detected signals versus time is clearly observed. Experimental testing proves that air bubbles can be successfully detected and counted. Their traveling speed can be estimated while simultaneously monitoring the refractive index of the fluid.
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spelling pubmed-104223032023-08-13 Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition Bello, Valentina Bodo, Elisabetta Merlo, Sabina Sensors (Basel) Article Detection of air bubbles in fluidic channels plays a fundamental role in all that medical equipment where liquids flow inside patients’ blood vessels or bodies. In this work, we propose a multi-parameter sensing system for simultaneous recognition of the fluid, on the basis of its refractive index and of the air bubble transit. The selected optofluidic platform has been designed and studied to be integrated into automatic pumps for the administration of commercial liquid. The sensor includes a laser beam that crosses twice a plastic cuvette, provided with a back mirror, and a position-sensitive detector. The identification of fluids is carried out by measuring the displacement of the output beam on the detector active surface and the detection of single air bubbles can be performed with the same instrumental scheme, exploiting a specific signal analysis. When a bubble, traveling along the cuvette, crosses the readout light beam, radiation is strongly scattered and a characteristic fingerprint shape of the photo-detected signals versus time is clearly observed. Experimental testing proves that air bubbles can be successfully detected and counted. Their traveling speed can be estimated while simultaneously monitoring the refractive index of the fluid. MDPI 2023-07-26 /pmc/articles/PMC10422303/ /pubmed/37571470 http://dx.doi.org/10.3390/s23156684 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bello, Valentina
Bodo, Elisabetta
Merlo, Sabina
Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title_full Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title_fullStr Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title_full_unstemmed Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title_short Optical Multi-Parameter Measuring System for Fluid and Air Bubble Recognition
title_sort optical multi-parameter measuring system for fluid and air bubble recognition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422303/
https://www.ncbi.nlm.nih.gov/pubmed/37571470
http://dx.doi.org/10.3390/s23156684
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