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Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications

Chitosan is a polysaccharide with film-forming properties. Such properties are widely used for the preparation of beauty masks and wound-healing materials. In this work, chitosan-based films containing hyaluronic acid and rutin have been researched for potential cosmetic applications. Rutin was adde...

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Detalles Bibliográficos
Autores principales: Sionkowska, Alina, Lewandowska, Katarzyna, Kurzawa, Marzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422548/
https://www.ncbi.nlm.nih.gov/pubmed/37571118
http://dx.doi.org/10.3390/polym15153224
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author Sionkowska, Alina
Lewandowska, Katarzyna
Kurzawa, Marzanna
author_facet Sionkowska, Alina
Lewandowska, Katarzyna
Kurzawa, Marzanna
author_sort Sionkowska, Alina
collection PubMed
description Chitosan is a polysaccharide with film-forming properties. Such properties are widely used for the preparation of beauty masks and wound-healing materials. In this work, chitosan-based films containing hyaluronic acid and rutin have been researched for potential cosmetic applications. Rutin was added to a chitosan solution in lactic acid, and then thin films were fabricated. The structure of the films was studied using FTIR spectroscopy. Surface properties were studied using an AFM microscope. The release of rutin from chitosan-based film was researched by the HPLC method. The properties of the skin, such as elasticity and moisturization, were studied using the Aramo TS 2 apparatus. It was found that the addition of rutin did not have an influence on the chitosan structure but affected its thermal stability. The roughness of the films was bigger after the addition of rutin to chitosan-based films. Skin elasticity and skin moisturization were somewhat improved after the topical application of the proposed chitosan–rutin mask. The maximum release of rutin was found after 20 min at pH 5.5, related to the pH of normal human skin. The average percentage of release from chitosan-based film containing hyaluronic acid was smaller than from chitosan-based films.
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spelling pubmed-104225482023-08-13 Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications Sionkowska, Alina Lewandowska, Katarzyna Kurzawa, Marzanna Polymers (Basel) Article Chitosan is a polysaccharide with film-forming properties. Such properties are widely used for the preparation of beauty masks and wound-healing materials. In this work, chitosan-based films containing hyaluronic acid and rutin have been researched for potential cosmetic applications. Rutin was added to a chitosan solution in lactic acid, and then thin films were fabricated. The structure of the films was studied using FTIR spectroscopy. Surface properties were studied using an AFM microscope. The release of rutin from chitosan-based film was researched by the HPLC method. The properties of the skin, such as elasticity and moisturization, were studied using the Aramo TS 2 apparatus. It was found that the addition of rutin did not have an influence on the chitosan structure but affected its thermal stability. The roughness of the films was bigger after the addition of rutin to chitosan-based films. Skin elasticity and skin moisturization were somewhat improved after the topical application of the proposed chitosan–rutin mask. The maximum release of rutin was found after 20 min at pH 5.5, related to the pH of normal human skin. The average percentage of release from chitosan-based film containing hyaluronic acid was smaller than from chitosan-based films. MDPI 2023-07-28 /pmc/articles/PMC10422548/ /pubmed/37571118 http://dx.doi.org/10.3390/polym15153224 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sionkowska, Alina
Lewandowska, Katarzyna
Kurzawa, Marzanna
Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title_full Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title_fullStr Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title_full_unstemmed Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title_short Chitosan-Based Films Containing Rutin for Potential Cosmetic Applications
title_sort chitosan-based films containing rutin for potential cosmetic applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422548/
https://www.ncbi.nlm.nih.gov/pubmed/37571118
http://dx.doi.org/10.3390/polym15153224
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