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Efficacy and safety of the endothelin-1 receptor antagonist macitentan in epicardial and microvascular vasospasm; a proof-of-concept study
BACKGROUND: Treatment of patients diagnosed with angina due to epicardial or microvascular coronary artery spasm (CAS) is challenging because patients often remain symptomatic despite conventional pharmacological therapy. In this prospective, randomized, double-blind, placebo-controlled, sequential...
Autores principales: | Feenstra, Rutger G.T., Jansen, Tijn P.J., Matthijs Boekholdt, S., Brouwer, Janet E., Klees, Margriet I., Appelman, Yolande, Wittekoek, Marianne E., van de Hoef, Tim P., de Winter, Robbert J., Piek, Jan J., Damman, Peter, Beijk, Marcel A.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422675/ https://www.ncbi.nlm.nih.gov/pubmed/37576078 http://dx.doi.org/10.1016/j.ijcha.2023.101238 |
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