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Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed
INTRODUCTION: The spleen is a responsible significant part of the immune system; after Splenectomy following trauma, the immune system changes; splenic autotransplantation can preserve the immune system after trauma and Splenectomy. BACKGROUND: Patients can be protected from immune dysfunction by au...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422790/ https://www.ncbi.nlm.nih.gov/pubmed/37568135 http://dx.doi.org/10.1186/s12893-023-02126-z |
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author | Saad, Hassan A. Elsayed, Rasha S Riad, Mohamed El-Taher, Ahmed K. Eraky, Mohamed E Abdelmonem, Ashraf |
author_facet | Saad, Hassan A. Elsayed, Rasha S Riad, Mohamed El-Taher, Ahmed K. Eraky, Mohamed E Abdelmonem, Ashraf |
author_sort | Saad, Hassan A. |
collection | PubMed |
description | INTRODUCTION: The spleen is a responsible significant part of the immune system; after Splenectomy following trauma, the immune system changes; splenic autotransplantation can preserve the immune system after trauma and Splenectomy. BACKGROUND: Patients can be protected from immune dysfunction by autotransplanting splenic tissues after splenectomy following trauma because their immune systems and spleens are changed. Patients can gain their immune function after splenic autotransplantation. METHODS: Patient classification methods are into three categories, Group A, 6 cases with auto-translation; Group B, 6 cases without transplantation; Group C, seven regular people serving as the control. AIM OF WORK: The aim of the work is not to compare outcome methods or compare types of autotransplantation; This work aims to document postoperative radiological, immunological, clinical, and hematological investigations. We concentrated on the results of investigations more than the types of operation or approach or types of autotransplantation. RESULTS: We showed that, after comparing each group with normal individuals subjects, patients who did not undergo autotransplantation had significantly higher platelet counts, a more significant percentage of micronucleated reticulocytes, increased levels of naive B lymphocytes, changes in class-switched memory and class-unswitched memory B cells, and higher levels of PD1 on CD8 + T lymphocytes. Nevertheless, neither splenic autotransplant patients nor the average general population showed any appreciable variations in any of the parameters. CONCLUSIONS: Spleen’s activities with adequate hemocatheter activity and recovery of the immunological deficit after splenic autotransplantation. |
format | Online Article Text |
id | pubmed-10422790 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104227902023-08-13 Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed Saad, Hassan A. Elsayed, Rasha S Riad, Mohamed El-Taher, Ahmed K. Eraky, Mohamed E Abdelmonem, Ashraf BMC Surg Research INTRODUCTION: The spleen is a responsible significant part of the immune system; after Splenectomy following trauma, the immune system changes; splenic autotransplantation can preserve the immune system after trauma and Splenectomy. BACKGROUND: Patients can be protected from immune dysfunction by autotransplanting splenic tissues after splenectomy following trauma because their immune systems and spleens are changed. Patients can gain their immune function after splenic autotransplantation. METHODS: Patient classification methods are into three categories, Group A, 6 cases with auto-translation; Group B, 6 cases without transplantation; Group C, seven regular people serving as the control. AIM OF WORK: The aim of the work is not to compare outcome methods or compare types of autotransplantation; This work aims to document postoperative radiological, immunological, clinical, and hematological investigations. We concentrated on the results of investigations more than the types of operation or approach or types of autotransplantation. RESULTS: We showed that, after comparing each group with normal individuals subjects, patients who did not undergo autotransplantation had significantly higher platelet counts, a more significant percentage of micronucleated reticulocytes, increased levels of naive B lymphocytes, changes in class-switched memory and class-unswitched memory B cells, and higher levels of PD1 on CD8 + T lymphocytes. Nevertheless, neither splenic autotransplant patients nor the average general population showed any appreciable variations in any of the parameters. CONCLUSIONS: Spleen’s activities with adequate hemocatheter activity and recovery of the immunological deficit after splenic autotransplantation. BioMed Central 2023-08-11 /pmc/articles/PMC10422790/ /pubmed/37568135 http://dx.doi.org/10.1186/s12893-023-02126-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Saad, Hassan A. Elsayed, Rasha S Riad, Mohamed El-Taher, Ahmed K. Eraky, Mohamed E Abdelmonem, Ashraf Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title | Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title_full | Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title_fullStr | Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title_full_unstemmed | Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title_short | Revitalize splenic functions. Following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
title_sort | revitalize splenic functions. following a splenectomy for trauma, a small amount of splenic autotransplantation was performed |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422790/ https://www.ncbi.nlm.nih.gov/pubmed/37568135 http://dx.doi.org/10.1186/s12893-023-02126-z |
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