STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway

Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in mPCa. Here we show a frequent genomic co-deletion of PTEN an...

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Detalles Bibliográficos
Autores principales: Pencik, Jan, Philippe, Cecile, Schlederer, Michaela, Atas, Emine, Pecoraro, Matteo, Grund-Gröschke, Sandra, Li, Wen (Jess), Tracz, Amanda, Heidegger, Isabel, Lagger, Sabine, Trachtová, Karolína, Oberhuber, Monika, Heitzer, Ellen, Aksoy, Osman, Neubauer, Heidi A., Wingelhofer, Bettina, Orlova, Anna, Witzeneder, Nadine, Dillinger, Thomas, Redl, Elisa, Greiner, Georg, D’Andrea, David, Östman, Johnny R., Tangermann, Simone, Hermanova, Ivana, Schäfer, Georg, Sternberg, Felix, Pohl, Elena E., Sternberg, Christina, Varady, Adam, Horvath, Jaqueline, Stoiber, Dagmar, Malcolm, Tim I., Turner, Suzanne D., Parkes, Eileen E., Hantusch, Brigitte, Egger, Gerda, Rose-John, Stefan, Poli, Valeria, Jain, Suneil, Armstrong, Chris W. D., Hoermann, Gregor, Goffin, Vincent, Aberger, Fritz, Moriggl, Richard, Carracedo, Arkaitz, McKinney, Cathal, Kennedy, Richard D., Klocker, Helmut, Speicher, Michael R., Tang, Dean G., Moazzami, Ali A., Heery, David M., Hacker, Marcus, Kenner, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422794/
https://www.ncbi.nlm.nih.gov/pubmed/37573301
http://dx.doi.org/10.1186/s12943-023-01825-8

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