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Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic

Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electr...

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Autores principales: Vella, Claire, Parvez, Wadood, Ashraf, Asif, Ajmal, Syed, Sudhir, Rajini, Agrawal, Sanjay, Bennett, Jonathan, Tufail, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422907/
https://www.ncbi.nlm.nih.gov/pubmed/37564035
http://dx.doi.org/10.1177/14799731231157770
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author Vella, Claire
Parvez, Wadood
Ashraf, Asif
Ajmal, Syed
Sudhir, Rajini
Agrawal, Sanjay
Bennett, Jonathan
Tufail, Muhammad
author_facet Vella, Claire
Parvez, Wadood
Ashraf, Asif
Ajmal, Syed
Sudhir, Rajini
Agrawal, Sanjay
Bennett, Jonathan
Tufail, Muhammad
author_sort Vella, Claire
collection PubMed
description Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electronic databases and hospital records were used to identify all patients diagnosed with lung cancer in 2018 (pre-LOLCP), 2019 (post-LOLCP), and March 2020–2021 (post-COVID-19 lockdown). Information regarding patient characteristics, performance status, stage, and route of diagnosis was documented and analysed. Emergency presentation was defined as diagnosis of new lung cancer being made after unscheduled attendance to urgent or emergency care facility. Results: Following implementation of the LOLCP pathway, there was a significant decrease in emergency presentations from 26.8 to 19.6% (p = 0.002) with a stage shift from 33.9% early stage disease to 40.3%. These improved outcomes were annulled during the COVID-19 pandemic, with emergency presentations increasing to 38.9% (p < 0.001) and a reduction in early-stage lung cancer diagnoses to 31.5%. There was a 61% decline in 2 week wait referrals but no significant decline in the LOLCP direct-to-CT referrals. Conclusion: We have demonstrated a significant increase in late-stage lung cancer diagnoses and emergency presentations during the first year of the COVID-19 pandemic. The causes for these changes are likely to be multifactorial. The long-term effect on lung cancer mortality remains to be seen and is an important focus of future study.
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spelling pubmed-104229072023-08-13 Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic Vella, Claire Parvez, Wadood Ashraf, Asif Ajmal, Syed Sudhir, Rajini Agrawal, Sanjay Bennett, Jonathan Tufail, Muhammad Chron Respir Dis COVID-19 and Chronic Respiratory Disease - Original Paper Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electronic databases and hospital records were used to identify all patients diagnosed with lung cancer in 2018 (pre-LOLCP), 2019 (post-LOLCP), and March 2020–2021 (post-COVID-19 lockdown). Information regarding patient characteristics, performance status, stage, and route of diagnosis was documented and analysed. Emergency presentation was defined as diagnosis of new lung cancer being made after unscheduled attendance to urgent or emergency care facility. Results: Following implementation of the LOLCP pathway, there was a significant decrease in emergency presentations from 26.8 to 19.6% (p = 0.002) with a stage shift from 33.9% early stage disease to 40.3%. These improved outcomes were annulled during the COVID-19 pandemic, with emergency presentations increasing to 38.9% (p < 0.001) and a reduction in early-stage lung cancer diagnoses to 31.5%. There was a 61% decline in 2 week wait referrals but no significant decline in the LOLCP direct-to-CT referrals. Conclusion: We have demonstrated a significant increase in late-stage lung cancer diagnoses and emergency presentations during the first year of the COVID-19 pandemic. The causes for these changes are likely to be multifactorial. The long-term effect on lung cancer mortality remains to be seen and is an important focus of future study. SAGE Publications 2023-08-11 /pmc/articles/PMC10422907/ /pubmed/37564035 http://dx.doi.org/10.1177/14799731231157770 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle COVID-19 and Chronic Respiratory Disease - Original Paper
Vella, Claire
Parvez, Wadood
Ashraf, Asif
Ajmal, Syed
Sudhir, Rajini
Agrawal, Sanjay
Bennett, Jonathan
Tufail, Muhammad
Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title_full Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title_fullStr Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title_full_unstemmed Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title_short Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
title_sort changes in lung cancer staging and emergency presentations during the first year of the covid-19 pandemic
topic COVID-19 and Chronic Respiratory Disease - Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422907/
https://www.ncbi.nlm.nih.gov/pubmed/37564035
http://dx.doi.org/10.1177/14799731231157770
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