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Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic
Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422907/ https://www.ncbi.nlm.nih.gov/pubmed/37564035 http://dx.doi.org/10.1177/14799731231157770 |
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author | Vella, Claire Parvez, Wadood Ashraf, Asif Ajmal, Syed Sudhir, Rajini Agrawal, Sanjay Bennett, Jonathan Tufail, Muhammad |
author_facet | Vella, Claire Parvez, Wadood Ashraf, Asif Ajmal, Syed Sudhir, Rajini Agrawal, Sanjay Bennett, Jonathan Tufail, Muhammad |
author_sort | Vella, Claire |
collection | PubMed |
description | Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electronic databases and hospital records were used to identify all patients diagnosed with lung cancer in 2018 (pre-LOLCP), 2019 (post-LOLCP), and March 2020–2021 (post-COVID-19 lockdown). Information regarding patient characteristics, performance status, stage, and route of diagnosis was documented and analysed. Emergency presentation was defined as diagnosis of new lung cancer being made after unscheduled attendance to urgent or emergency care facility. Results: Following implementation of the LOLCP pathway, there was a significant decrease in emergency presentations from 26.8 to 19.6% (p = 0.002) with a stage shift from 33.9% early stage disease to 40.3%. These improved outcomes were annulled during the COVID-19 pandemic, with emergency presentations increasing to 38.9% (p < 0.001) and a reduction in early-stage lung cancer diagnoses to 31.5%. There was a 61% decline in 2 week wait referrals but no significant decline in the LOLCP direct-to-CT referrals. Conclusion: We have demonstrated a significant increase in late-stage lung cancer diagnoses and emergency presentations during the first year of the COVID-19 pandemic. The causes for these changes are likely to be multifactorial. The long-term effect on lung cancer mortality remains to be seen and is an important focus of future study. |
format | Online Article Text |
id | pubmed-10422907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-104229072023-08-13 Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic Vella, Claire Parvez, Wadood Ashraf, Asif Ajmal, Syed Sudhir, Rajini Agrawal, Sanjay Bennett, Jonathan Tufail, Muhammad Chron Respir Dis COVID-19 and Chronic Respiratory Disease - Original Paper Aim: This study retrospectively analyses the impact of the 1(st) year of the COVID-19 pandemic on route of presentation and staging in lung cancer compared to the 2 years before and after implementation of the Leicester Optimal Lung Cancer Pathway (LOLCP) in Leicester, United Kingdom. Method: Electronic databases and hospital records were used to identify all patients diagnosed with lung cancer in 2018 (pre-LOLCP), 2019 (post-LOLCP), and March 2020–2021 (post-COVID-19 lockdown). Information regarding patient characteristics, performance status, stage, and route of diagnosis was documented and analysed. Emergency presentation was defined as diagnosis of new lung cancer being made after unscheduled attendance to urgent or emergency care facility. Results: Following implementation of the LOLCP pathway, there was a significant decrease in emergency presentations from 26.8 to 19.6% (p = 0.002) with a stage shift from 33.9% early stage disease to 40.3%. These improved outcomes were annulled during the COVID-19 pandemic, with emergency presentations increasing to 38.9% (p < 0.001) and a reduction in early-stage lung cancer diagnoses to 31.5%. There was a 61% decline in 2 week wait referrals but no significant decline in the LOLCP direct-to-CT referrals. Conclusion: We have demonstrated a significant increase in late-stage lung cancer diagnoses and emergency presentations during the first year of the COVID-19 pandemic. The causes for these changes are likely to be multifactorial. The long-term effect on lung cancer mortality remains to be seen and is an important focus of future study. SAGE Publications 2023-08-11 /pmc/articles/PMC10422907/ /pubmed/37564035 http://dx.doi.org/10.1177/14799731231157770 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | COVID-19 and Chronic Respiratory Disease - Original Paper Vella, Claire Parvez, Wadood Ashraf, Asif Ajmal, Syed Sudhir, Rajini Agrawal, Sanjay Bennett, Jonathan Tufail, Muhammad Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title | Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title_full | Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title_fullStr | Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title_full_unstemmed | Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title_short | Changes in lung cancer staging and emergency presentations during the first year of the COVID-19 pandemic |
title_sort | changes in lung cancer staging and emergency presentations during the first year of the covid-19 pandemic |
topic | COVID-19 and Chronic Respiratory Disease - Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422907/ https://www.ncbi.nlm.nih.gov/pubmed/37564035 http://dx.doi.org/10.1177/14799731231157770 |
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