Evolutionary potential of the monkeypox genome arising from interactions with human APOBEC3 enzymes

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APOBEC3, an enzyme subfamily that plays a role in virus restriction by generating mutations at particular DNA motifs or mutational ‘hotspots’, can drive viral mutagenesis with host-specific preferential hotspot mutations contributing to pathogen variation. While previous analysis of viral genomes fr...

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Detalles Bibliográficos
Autores principales: Delamonica, Brenda, Davalos, Liliana, Larijani, Mani, Anthony, Simon J, Liu, Jia, MacCarthy, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422979/
https://www.ncbi.nlm.nih.gov/pubmed/37577211
http://dx.doi.org/10.1093/ve/vead047
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