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Postsynaptic Calcium Extrusion at the Mouse Neuromuscular Junction Alkalinizes the Synaptic Cleft

Neurotransmission is shaped by extracellular pH. Alkalization enhances pH-sensitive transmitter release and receptor activation, whereas acidification inhibits these processes and can activate acid-sensitive conductances in the synaptic cleft. Previous work has shown that the synaptic cleft can eith...

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Detalles Bibliográficos
Autores principales: Durbin, Ryan J., Heredia, Dante J., Gould, Thomas W., Renden, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423045/
https://www.ncbi.nlm.nih.gov/pubmed/37474311
http://dx.doi.org/10.1523/JNEUROSCI.0815-23.2023