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Association of CDKN2A/B mutations, PD-1, and PD-L1 with the risk of acute lymphoblastic leukemia in children

PURPOSE: Currently, the significance of CDKN2A/B mutations in the pathogenesis and prognosis of acute lymphoblastic leukemia (ALL) is inconclusive. In this study, we analyzed the genetic and clinical features of children with CDKN2A/B mutations in ALL. In addition, we evaluated the expression and si...

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Detalles Bibliográficos
Autores principales: Ruan, Yang, Xie, Longlong, Zou, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423156/
https://www.ncbi.nlm.nih.gov/pubmed/37314514
http://dx.doi.org/10.1007/s00432-023-04974-x