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E4orf1 improves adipose tissue-specific metabolic risk factors and indicators of cognition function in a mouse model of Alzheimer’s disease

OBJECTIVE: Obesity, impaired glycemic control, and hepatic steatosis often coexist and are risk factors for developing dementia, and Alzheimer’s disease (AD). We hypothesized that a therapeutic agent that improves glycemic control and steatosis may attenuate obesity-associated progression of dementi...

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Detalles Bibliográficos
Autores principales:	Khan, Md Shahjalal Hossain, Hefner, Marleigh, Reddy, Arubala, Dhurandhar, Nikhil V., Hegde, Vijay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423203/ https://www.ncbi.nlm.nih.gov/pubmed/37573386 http://dx.doi.org/10.1038/s41387-023-00242-6

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