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Self-anticoagulant sponge for whole blood auto-transfusion and its mechanism of coagulation factor inactivation

Clinical use of intraoperative auto-transfusion requires the removal of platelets and plasma proteins due to pump-based suction and water-soluble anticoagulant administration, which causes dilutional coagulopathy. Herein, we develop a carboxylated and sulfonated heparin-mimetic polymer-modified spon...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Ji, Haifeng, Xu, Lin, Cheng, Shengjun, Liu, Xianda, Li, Yupei, Zhong, Rui, Zhao, Weifeng, Kizhakkedathu, Jayachandran N., Zhao, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423252/
https://www.ncbi.nlm.nih.gov/pubmed/37573353
http://dx.doi.org/10.1038/s41467-023-40646-7