Cargando…

Deubiquitinase YOD1 suppresses tumor progression by stabilizing E3 ligase TRIM33 in head and neck squamous cell carcinoma

Ubiquitination is a reversible process that not only controls protein synthesis and degradation, but also is essential for protein transport, localization and biological activity. Deubiquitinating enzyme (DUB) dysfunction leads to various diseases, including cancer. In this study, we aimed to explor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yue, Duan, Yuansheng, Han, Wei, Cao, Jiayan, Ye, Beibei, Chen, Peng, Li, Hong, Wang, Yuxuan, Liu, Jin, Fang, Yan, Yue, Kai, Wu, Yansheng, Wang, Xudong, Jing, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423255/ https://www.ncbi.nlm.nih.gov/pubmed/37573347 http://dx.doi.org/10.1038/s41419-023-06035-0

Ejemplares similares

Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer
por: Kim, Youngeun, et al.
Publicado: (2017)

JOSD1 promotes proliferation and chemoresistance of head and neck squamous cell carcinoma under the epigenetic regulation of BRD4
por: Jing, Chao, et al.
Publicado: (2021)

Identification of novel hub genes associated with lymph node metastasis of head and neck squamous cell carcinoma by completive bioinformatics analysis
por: Lu, Honglue, et al.
Publicado: (2021)

LncRNA MALAT1 promotes growth and metastasis of head and neck squamous cell carcinoma by repressing VHL through a non-canonical function of EZH2
por: Duan, Yuansheng, et al.
Publicado: (2023)

Correction: LncRNA MALAT1 promotes growth and metastasis of head and neck squamous cell carcinoma by repressing VHL through a non-canonical function of EZH2
por: Duan, Yuansheng, et al.
Publicado: (2023)

Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells
por: Shao, Xuejing, et al.
Publicado: (2022)

miR-221/222 induce instability of p53 By downregulating deubiquitinase YOD1 in acute myeloid leukemia
por: Pei, Han Zhong, et al.
Publicado: (2023)

Development and Validation of a Nomogram based on cell growth-related Biomarkers for Oral Squamous Cell Carcinoma
por: Shuai, Yanjie, et al.
Publicado: (2021)

Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness
por: Jing, Chao, et al.
Publicado: (2021)

Pattern and Predictive Factors of Metastasis in Lymph Nodes Posterior to the Right Recurrent Laryngeal Nerve in Papillary Thyroid Carcinoma
por: Zhou, Mengqian, et al.
Publicado: (2022)

Clinical characteristics and outcomes of cervical lymph node metastasis from unknown primary sites: a single institution’s 14-year experience
por: Zhou, Mengqian, et al.
Publicado: (2023)

Detection of thyroglobulin in fine-needle aspiration for diagnosis of metastatic lateral cervical lymph nodes in papillary thyroid carcinoma: A retrospective study
por: Wang, Yuxuan, et al.
Publicado: (2022)

[Retracted] microRNA‑7 regulates cell growth, migration and invasion via direct targeting of PAK1 in thyroid cancer
por: Yue, Kai, et al.
Publicado: (2023)

The PSMD14 inhibitor Thiolutin as a novel therapeutic approach for esophageal squamous cell carcinoma through facilitating SNAIL degradation
por: Jing, Chao, et al.
Publicado: (2021)

Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma
por: Li, Xiaomei, et al.
Publicado: (2021)

The role of E3 ubiquitin ligases and deubiquitinases in bladder cancer development and immunotherapy
por: Wang, Xuemei, et al.
Publicado: (2023)

Prognostic significance of pre-treatment serum Cyfra21-1 as a tumor marker in patients with oropharyngeal squamous cell carcinoma treated with concurrent chemoradiotherapy
por: Li, Liang, et al.
Publicado: (2020)

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer
por: Shiromizu, Takashi, et al.
Publicado: (2020)

YOD1 serves as a potential prognostic biomarker for pancreatic cancer
por: Zhang, Zhishuo, et al.
Publicado: (2022)

Synergistic effect of YOD1 and USP21 on the Hippo signaling pathway
por: Park, Sang-Soo, et al.
Publicado: (2023)

Prognostic role of pre-treatment serum ALB in Patients with oropharyngeal cancer: A retrospective cohort study
por: Zhu, Jiajia, et al.
Publicado: (2022)

Origin and Diversification of TRIM Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2012)

Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56
por: Xue, Min, et al.
Publicado: (2019)

Structural insights into the TRIM family of ubiquitin E3 ligases
por: Li, Yang, et al.
Publicado: (2014)

Overexpression of TRIM24 Stimulates Proliferation and Glucose Metabolism of Head and Neck Squamous Cell Carcinoma
por: Wang, Hongming, et al.
Publicado: (2018)

E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapies
por: Wang, Maoyu, et al.
Publicado: (2023)

THE DIMENSIONS OF YOUNG ONSET DEMENTIA (YOD) AND WHAT THESE MEAN FOR EXTENDED WORKING LIVES
por: Taylor, Philip
Publicado: (2022)

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification
por: Nicklas, Sarah, et al.
Publicado: (2018)

Deep-learning based approach to identify substrates of human E3 ubiquitin ligases and deubiquitinases
por: Shu, Yixuan, et al.
Publicado: (2023)

Involvement of E3 Ligases and Deubiquitinases in the Control of HIF-α Subunit Abundance
por: Kubaichuk, Kateryna, et al.
Publicado: (2019)

Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants
por: Gorelik, Maryna, et al.
Publicado: (2016)

Differential Regulation of Myocardial E3 Ligases and Deubiquitinases in Ischemic Heart Failure
por: Klaeske, Kristin, et al.
Publicado: (2021)

The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33
por: Ni, Yingmeng, et al.
Publicado: (2015)

Deubiquitylase YOD1 regulates CDK1 stability and drives triple-negative breast cancer tumorigenesis
por: Han, Zhitao, et al.
Publicado: (2023)

Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains
por: Sekirnik, Angelina R., et al.
Publicado: (2022)

TRIM32 is an E3 ubiquitin ligase for dysbindin
por: Locke, Matthew, et al.
Publicado: (2009)

Hypoxia induced Bcl-2/Twist1 complex promotes tumor cell invasion in oral squamous cell carcinoma
por: Duan, Yuansheng, et al.
Publicado: (2016)

Pre-treatment circulating neutrophil count is an independent prognostic factor in oropharyngeal cancer
por: Li, Liang, et al.
Publicado: (2020)

Surgical Extent of Central Lymph Node Dissection for Papillary Thyroid Carcinoma Located in the Isthmus: A Propensity Scoring Matched Study
por: Shuai, Yanjie, et al.
Publicado: (2021)

The Role of E3 Ubiquitin Ligases and Deubiquitinases in Inflammatory Bowel Disease: Friend or Foe?
por: Zou, Min, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aol0p1s8lb5oe4k46r1b2rj5vq