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Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis

OBJECTIVES: The activator protein-1 (AP-1) transcription factor component c-Fos regulates chondrocyte proliferation and differentiation, but its involvement in osteoarthritis (OA) has not been functionally assessed. METHODS: c-Fos expression was evaluated by immunohistochemistry on articular cartila...

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Detalles Bibliográficos
Autores principales: Matsuoka, Kazuhiko, Bakiri, Latifa, Bilban, Martin, Toegel, Stefan, Haschemi, Arvand, Yuan, Hao, Kasper, Maria, Windhager, Reinhard, Wagner, Erwin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423482/
https://www.ncbi.nlm.nih.gov/pubmed/37344157
http://dx.doi.org/10.1136/ard-2023-224002