NRX-101 (D-cycloserine plus lurasidone) vs. lurasidone for the maintenance of initial stabilization after ketamine in patients with severe bipolar depression with acute suicidal ideation and behavior: a randomized prospective phase 2 trial

BACKGROUND: We tested the hypothesis that, after initial improvement with intravenous ketamine in patients with bipolar disorder (BD) with severe depression and acute suicidal thinking or behavior, a fixed-dose combination of oral D-cycloserine (DCS) and lurasidone (NRX-101) can maintain improvement...

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Detalles Bibliográficos
Autores principales: Nierenberg, Andrew, Lavin, Philip, Javitt, Daniel C., Shelton, Richard, Sapko, Michael T., Mathew, Sanjay, Besthof, Robert E., Javitt, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423711/
https://www.ncbi.nlm.nih.gov/pubmed/37573534
http://dx.doi.org/10.1186/s40345-023-00308-5

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