Cargando…

Age-, sex-, and pathology-related variability in brain structure and cognition

This work aimed to investigate potential pathways linking age and imaging measures to early age- and pathology-related changes in cognition. We used [18F]-Flutemetamol (amyloid) and [18F]-Flortaucipir (tau) positron emission tomography (PET), structural MRI, and neuropsychological assessment from 23...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bachmann, Dario, Buchmann, Andreas, Studer, Sandro, Saake, Antje, Rauen, Katrin, Zuber, Isabelle, Gruber, Esmeralda, Nitsch, Roger M., Hock, Christoph, Gietl, Anton, Treyer, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423720/ https://www.ncbi.nlm.nih.gov/pubmed/37574523 http://dx.doi.org/10.1038/s41398-023-02572-6

Ejemplares similares

Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women
por: Bachmann, Dario, et al.
Publicado: (2022)

Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience–a study in exceptional aging
por: Treyer, Valerie, et al.
Publicado: (2021)

Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia
por: Treyer, Valerie, et al.
Publicado: (2020)

Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly
por: Zhang, Junhao, et al.
Publicado: (2023)

Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4
por: Quevenco, Frances C., et al.
Publicado: (2020)

Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System
por: Steininger, Stefanie C., et al.
Publicado: (2014)

Intraindividual variability across cognitive tasks as a potential marker for prodromal Alzheimer’s disease
por: Kälin, Andrea M., et al.
Publicado: (2014)

APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults
por: Kagerer, Sonja M., et al.
Publicado: (2020)

Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects
por: Schreiner, Simon J., et al.
Publicado: (2014)

ATN profile classification across two independent prospective cohorts
por: Peretti, Débora E., et al.
Publicado: (2023)

Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography
por: Laurig, Mathias, et al.
Publicado: (2013)

Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age
por: Kagerer, Sonja M., et al.
Publicado: (2022)

Tauvid™: The First FDA-Approved PET Tracer for Imaging Tau Pathology in Alzheimer’s Disease
por: Jie, Caitlin V. M. L., et al.
Publicado: (2021)

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment
por: van Bergen, J. M. G., et al.
Publicado: (2016)

Brain areas with normatively greater cerebral perfusion in early life may be more susceptible to beta amyloid deposition in late life
por: Meier, Irene B., et al.
Publicado: (2020)

Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients
por: Kälin, Andrea M., et al.
Publicado: (2017)

Early termination of pivotal trials in Alzheimer's disease—Preserving optimal value for participants and science
por: Gietl, Anton F., et al.
Publicado: (2022)

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer’s disease
por: Quevenco, Frances C., et al.
Publicado: (2017)

EEG-fMRI Signal Coupling Is Modulated in Subjects With Mild Cognitive Impairment and Amyloid Deposition
por: Michels, Lars, et al.
Publicado: (2021)

Development of VariLeg, an exoskeleton with variable stiffness actuation: first results and user evaluation from the CYBATHLON 2016
por: Schrade, Stefan O., et al.
Publicado: (2018)

Maize Silage Pretreatment via Steam Refining and Subsequent Enzymatic Hydrolysis for the Production of Fermentable Carbohydrates
por: Krafft, Malte Jörn, et al.
Publicado: (2020)

Lesion evidence for a causal role of the insula in aversion to social inequity
por: Nitsch, Felix Jan, et al.
Publicado: (2021)

Folgen der COVID-19-Pandemie für Menschen mit Schizophrenie, Demenz und Abhängigkeitserkrankungen
por: Adorjan, Kristina, et al.
Publicado: (2021)

Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment
por: Michels, Lars, et al.
Publicado: (2017)

Impact of scanner variability on lymph node segmentation in computational pathology
por: Khan, Amjad, et al.
Publicado: (2022)

Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation
por: Riese, Florian, et al.
Publicado: (2013)

Quality of life after traumatic brain injury: a cross-sectional analysis uncovers age- and sex-related differences over the adult life span
por: Rauen, Katrin, et al.
Publicado: (2020)

Postoperative IMRT in head and neck cancer
por: Studer, Gabriela, et al.
Publicado: (2006)

Sex differences in interindividual gene expression variability across human tissues
por: Khodursky, Samuel, et al.
Publicado: (2022)

Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer’s disease-related microvascular cerebral amyloid angiopathy
por: Merlini, Mario, et al.
Publicado: (2016)

Accelerometric Trunk Sensors to Detect Changes of Body Positions in Immobile Patients
por: Rauen, Katrin, et al.
Publicado: (2018)

Preservation of high resolution protein structure by cryo-electron microscopy of vitreous sections
por: Sader, Kasim, et al.
Publicado: (2009)

Accounting for sex differences variability in the design of sex-adapted cancer treatments
por: Yang, Wei, et al.
Publicado: (2023)

Fractionation of Waste MDF by Steam Refining
por: Hagel, Sebastian, et al.
Publicado: (2020)

Shapley variable importance cloud for interpretable machine learning
por: Ning, Yilin, et al.
Publicado: (2022)

Correlation‐adjusted regression survival scores for high‐dimensional variable selection
por: Welchowski, Thomas, et al.
Publicado: (2019)

Sensitivity of outcome instruments in a priori selected patient groups after traumatic brain injury: Results from the CENTER-TBI study
por: von Steinbuechel, Nicole, et al.
Publicado: (2023)

The Maunder minimum and the variable sun-earth connection
por: Wei Hock Soon, Willie, et al.
Publicado: (2003)

Psychopathological Symptom Load and Distinguishable Cerebral Blood Flow Velocity Patterns in Patients With Schizophrenia and Healthy Controls: A Functional Transcranial Doppler Study
por: Egger, Stephan T., et al.
Publicado: (2021)

Sex as an important biological variable in biomedical research
por: Lee, Suk Kyeong
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e8hofvqltq21hp8gepf85qa67h