Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized, double‐blind, parallel‐controlled clinical trial

Hyperhomocysteinemia with hypertension can synergistically increase the risk of stroke. The China stroke primary prevention trial showed that combining 0.8 mg folic acid (FA) with angiotensin‐converting enzyme inhibitor (ACEI) can effectively lower plasma total homocysteine (tHcy) and blood pressure...

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Detalles Bibliográficos
Autores principales: Bao, Huihui, Huang, Xiao, Li, Ping, Sheng, Changsheng, Zhang, Jin, Wang, Zhirong, Song, Demin, Hu, Lihua, Ding, Congcong, Cheng, Zaihua, Yao, Chen, Chen, Guangliang, Cui, Yimin, Qin, Xianhui, Tang, Genfu, Wang, Xiaobin, Huo, Yong, Cheng, Xiaoshu, Wang, Jiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423753/
https://www.ncbi.nlm.nih.gov/pubmed/37433173
http://dx.doi.org/10.1111/jch.14697

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