Cav3.2 T-Type calcium channels downregulation attenuates bone cancer pain induced by inhibiting IGF-1/HIF-1α signaling pathway in the rat spinal cord

BACKGROUND: Bone cancer pain (BCP) is one of the most ubiquitous and refractory symptoms of cancer patients that needs to be urgently addressed. Substantial studies have revealed the pivotal role of Cav3.2 T-type calcium channels in chronic pain, however, its involvement in BCP and the specific mole...

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Detalles Bibliográficos
Autores principales: Liu, Qingying, Lu, Zhongyuan, Ren, Huan, Fu, Lijun, Wang, Yueliang, Bu, Huilian, Ma, Minyu, Ma, Letian, Huang, Chen, Wang, Jian, Zang, Weidong, Cao, Jing, Fan, Xiaochong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423893/
https://www.ncbi.nlm.nih.gov/pubmed/37583441
http://dx.doi.org/10.1016/j.jbo.2023.100495

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