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pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy

Currently, the dynamic erosive small molecule nano-prodrug is of great demand for oral chemotherapy, owing to its precise structure, high drug loading and improved oral bioavailability via overcoming various physiologic barriers in gastrointestinal tract, blood circulation and tumor tissues compared...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Wang, Zhexiang, Ren, Xiaodie, Chen, Xinyang, Tao, Jinjin, Guan, Yuanhui, Yang, Xuefeng, Tang, Rupei, Yan, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423923/
https://www.ncbi.nlm.nih.gov/pubmed/37583708
http://dx.doi.org/10.1016/j.ajps.2023.100832

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