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pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy
Currently, the dynamic erosive small molecule nano-prodrug is of great demand for oral chemotherapy, owing to its precise structure, high drug loading and improved oral bioavailability via overcoming various physiologic barriers in gastrointestinal tract, blood circulation and tumor tissues compared...
Autores principales: | Liu, Xin, Wang, Zhexiang, Ren, Xiaodie, Chen, Xinyang, Tao, Jinjin, Guan, Yuanhui, Yang, Xuefeng, Tang, Rupei, Yan, Guoqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423923/ https://www.ncbi.nlm.nih.gov/pubmed/37583708 http://dx.doi.org/10.1016/j.ajps.2023.100832 |
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