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Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips

This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethy...

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Autores principales: Li, Yuqing, Zhang, Huimin, Li, Qian, Deng, Yuqin, Ye, Zi, Gui, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424060/
https://www.ncbi.nlm.nih.gov/pubmed/37583671
http://dx.doi.org/10.1039/d3ra04497a
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author Li, Yuqing
Zhang, Huimin
Li, Qian
Deng, Yuqin
Ye, Zi
Gui, Lin
author_facet Li, Yuqing
Zhang, Huimin
Li, Qian
Deng, Yuqin
Ye, Zi
Gui, Lin
author_sort Li, Yuqing
collection PubMed
description This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethylsiloxane (PDMS) slab with standard soft-lithography technology and bonded with another PDMS slab with microelectrode patterns on it. When injected with LM, the texture-like structure can prevent the LM from entering but allows the air inside to be released during the injection to achieve perfect blind-end complex LM electrodes. The experimental results show that it can achieve fast and perfect LM injection in the blind-end pattern and can also prevent the large area of the flat chamber from collapsing during bonding. We also parametrically studied the texture structure's size for bonding strength between the texture structure and the blank PDMS surface. In addition, we integrate three layers of blind-end complex liquid metal patterns into one multi-layer chip using this technology and later use this structure to realize series connection of two LM-based electroosmotic micropumps (EOP). Compared with the conventional LM-based EOP, the structure of the EOP chip was greatly simplified and resulted in a higher level of integration.
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spelling pubmed-104240602023-08-15 Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips Li, Yuqing Zhang, Huimin Li, Qian Deng, Yuqin Ye, Zi Gui, Lin RSC Adv Chemistry This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethylsiloxane (PDMS) slab with standard soft-lithography technology and bonded with another PDMS slab with microelectrode patterns on it. When injected with LM, the texture-like structure can prevent the LM from entering but allows the air inside to be released during the injection to achieve perfect blind-end complex LM electrodes. The experimental results show that it can achieve fast and perfect LM injection in the blind-end pattern and can also prevent the large area of the flat chamber from collapsing during bonding. We also parametrically studied the texture structure's size for bonding strength between the texture structure and the blank PDMS surface. In addition, we integrate three layers of blind-end complex liquid metal patterns into one multi-layer chip using this technology and later use this structure to realize series connection of two LM-based electroosmotic micropumps (EOP). Compared with the conventional LM-based EOP, the structure of the EOP chip was greatly simplified and resulted in a higher level of integration. The Royal Society of Chemistry 2023-08-14 /pmc/articles/PMC10424060/ /pubmed/37583671 http://dx.doi.org/10.1039/d3ra04497a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Yuqing
Zhang, Huimin
Li, Qian
Deng, Yuqin
Ye, Zi
Gui, Lin
Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title_full Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title_fullStr Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title_full_unstemmed Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title_short Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
title_sort texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424060/
https://www.ncbi.nlm.nih.gov/pubmed/37583671
http://dx.doi.org/10.1039/d3ra04497a
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AT dengyuqin texturestructurebasedliquidmetalfillingforblindendmicrochannelsanditsapplicationonmultilayerchips
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