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Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips
This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethy...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424060/ https://www.ncbi.nlm.nih.gov/pubmed/37583671 http://dx.doi.org/10.1039/d3ra04497a |
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author | Li, Yuqing Zhang, Huimin Li, Qian Deng, Yuqin Ye, Zi Gui, Lin |
author_facet | Li, Yuqing Zhang, Huimin Li, Qian Deng, Yuqin Ye, Zi Gui, Lin |
author_sort | Li, Yuqing |
collection | PubMed |
description | This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethylsiloxane (PDMS) slab with standard soft-lithography technology and bonded with another PDMS slab with microelectrode patterns on it. When injected with LM, the texture-like structure can prevent the LM from entering but allows the air inside to be released during the injection to achieve perfect blind-end complex LM electrodes. The experimental results show that it can achieve fast and perfect LM injection in the blind-end pattern and can also prevent the large area of the flat chamber from collapsing during bonding. We also parametrically studied the texture structure's size for bonding strength between the texture structure and the blank PDMS surface. In addition, we integrate three layers of blind-end complex liquid metal patterns into one multi-layer chip using this technology and later use this structure to realize series connection of two LM-based electroosmotic micropumps (EOP). Compared with the conventional LM-based EOP, the structure of the EOP chip was greatly simplified and resulted in a higher level of integration. |
format | Online Article Text |
id | pubmed-10424060 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-104240602023-08-15 Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips Li, Yuqing Zhang, Huimin Li, Qian Deng, Yuqin Ye, Zi Gui, Lin RSC Adv Chemistry This research work reports a novel method to achieve fast liquid metal (LM) injection in blind-end microchannels which is especially suitable for multi-layer microfluidic chips. This method is based on a texture-like surface bonding technology. The texture-like surface is fabricated on a polydimethylsiloxane (PDMS) slab with standard soft-lithography technology and bonded with another PDMS slab with microelectrode patterns on it. When injected with LM, the texture-like structure can prevent the LM from entering but allows the air inside to be released during the injection to achieve perfect blind-end complex LM electrodes. The experimental results show that it can achieve fast and perfect LM injection in the blind-end pattern and can also prevent the large area of the flat chamber from collapsing during bonding. We also parametrically studied the texture structure's size for bonding strength between the texture structure and the blank PDMS surface. In addition, we integrate three layers of blind-end complex liquid metal patterns into one multi-layer chip using this technology and later use this structure to realize series connection of two LM-based electroosmotic micropumps (EOP). Compared with the conventional LM-based EOP, the structure of the EOP chip was greatly simplified and resulted in a higher level of integration. The Royal Society of Chemistry 2023-08-14 /pmc/articles/PMC10424060/ /pubmed/37583671 http://dx.doi.org/10.1039/d3ra04497a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Li, Yuqing Zhang, Huimin Li, Qian Deng, Yuqin Ye, Zi Gui, Lin Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title | Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title_full | Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title_fullStr | Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title_full_unstemmed | Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title_short | Texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
title_sort | texture-structure-based liquid metal filling for blind-end microchannels and its application on multi-layer chips |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424060/ https://www.ncbi.nlm.nih.gov/pubmed/37583671 http://dx.doi.org/10.1039/d3ra04497a |
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