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Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Agal‐Pro BL/BL‐L®. The additive is a preparation of alpha‐galactosidase produced by a genetically modified strain of Saccharomyces cerevisiae (CBS 615....

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Anguita, Montserrat, Brozzi, Rosella, Ortuño, Jordi, Pettenati, Elisa, Tarrés‐Call, Jordi, García‐Cazorla, Yolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424062/
https://www.ncbi.nlm.nih.gov/pubmed/37583944
http://dx.doi.org/10.2903/j.efsa.2023.8175
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Anguita, Montserrat
Brozzi, Rosella
Ortuño, Jordi
Pettenati, Elisa
Tarrés‐Call, Jordi
García‐Cazorla, Yolanda
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Anguita, Montserrat
Brozzi, Rosella
Ortuño, Jordi
Pettenati, Elisa
Tarrés‐Call, Jordi
García‐Cazorla, Yolanda
collection PubMed
description Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Agal‐Pro BL/BL‐L®. The additive is a preparation of alpha‐galactosidase produced by a genetically modified strain of Saccharomyces cerevisiae (CBS 615.94) and endo‐1,4‐beta‐glucanase produced by a non‐genetically modified strain of Aspergillus niger (CBS 120604). It is intended to be used as a zootechnical additive (functional group: digestibility enhancers) in chickens for fattening in its solid and liquid forms (Agal‐Pro BL® and Agal‐Pro BL‐L®), and in minor poultry species for fattening and chickens reared for laying only in its solid form (Agal‐Pro BL®). The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There is no new evidence that would lead the FEEDAP Panel to reconsider its previous conclusions. Thus, the Panel concludes that the additive remains safe for the target animals, consumers and the environment under the authorised conditions of use. Regarding user safety, the additive is considered an irritant to the skin and eyes and a dermal sensitiser. Due to the proteinaceous nature of the active substances, it should be considered a respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.
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spelling pubmed-104240622023-08-15 Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Anguita, Montserrat Brozzi, Rosella Ortuño, Jordi Pettenati, Elisa Tarrés‐Call, Jordi García‐Cazorla, Yolanda EFSA J Scientific Opinion Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Agal‐Pro BL/BL‐L®. The additive is a preparation of alpha‐galactosidase produced by a genetically modified strain of Saccharomyces cerevisiae (CBS 615.94) and endo‐1,4‐beta‐glucanase produced by a non‐genetically modified strain of Aspergillus niger (CBS 120604). It is intended to be used as a zootechnical additive (functional group: digestibility enhancers) in chickens for fattening in its solid and liquid forms (Agal‐Pro BL® and Agal‐Pro BL‐L®), and in minor poultry species for fattening and chickens reared for laying only in its solid form (Agal‐Pro BL®). The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There is no new evidence that would lead the FEEDAP Panel to reconsider its previous conclusions. Thus, the Panel concludes that the additive remains safe for the target animals, consumers and the environment under the authorised conditions of use. Regarding user safety, the additive is considered an irritant to the skin and eyes and a dermal sensitiser. Due to the proteinaceous nature of the active substances, it should be considered a respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation. John Wiley and Sons Inc. 2023-08-14 /pmc/articles/PMC10424062/ /pubmed/37583944 http://dx.doi.org/10.2903/j.efsa.2023.8175 Text en © 2023 European Food Safety Authority. EFSA Journal published by Wiley‐VCH GmbH on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Anguita, Montserrat
Brozzi, Rosella
Ortuño, Jordi
Pettenati, Elisa
Tarrés‐Call, Jordi
García‐Cazorla, Yolanda
Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title_full Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title_fullStr Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title_full_unstemmed Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title_short Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (Kerry Ingredients & Flavours Ltd.)
title_sort assessment of the feed additive consisting of alpha‐galactosidase produced by saccharomyces cerevisiae cbs 615.94 and endo‐1,4‐beta‐glucanase produced by aspergillus niger cbs 120604 (agal‐pro bl/bl‐l®) for use in chickens for fattening, minor poultry species for fattening and chickens reared for laying for the renewal of its authorisation (kerry ingredients & flavours ltd.)
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424062/
https://www.ncbi.nlm.nih.gov/pubmed/37583944
http://dx.doi.org/10.2903/j.efsa.2023.8175
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