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Characterization of the human platelet N- and O-glycome upon storage using tandem mass spectrometry

Changes in surface glycan determinants, specifically sialic acid loss, determine platelet life span. The gradual loss of stored platelet quality is a complex process that fundamentally involves carbohydrate structures. Here, we applied lipophilic extraction and glycan release protocols to sequential...

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Detalles Bibliográficos
Autores principales: Rosenbalm, Katelyn E., Lee-Sundlov, Melissa M., Ashline, David J., Grozovsky, Renata, Aoki, Kazuhiro, Hanneman, Andrew J. S., Hoffmeister, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424148/
https://www.ncbi.nlm.nih.gov/pubmed/36952551
http://dx.doi.org/10.1182/bloodadvances.2022007084

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