C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein

[Image: see text] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, by infecting cells via the interaction of its spike protein (S) with the primary cell receptor angiotensin-converting enzyme (ACE2). To search for inhibitors of this key step in viral infection, we screen...

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Detalles Bibliográficos
Autores principales: Gargantilla, Marta, Francés, Clara, Adhav, Anmol, Forcada-Nadal, Alicia, Martínez-Gualda, Belén, Martí-Marí, Olaia, López-Redondo, María Luisa, Melero, Roberto, Marco-Marín, Clara, Gougeard, Nadine, Espinosa, Carolina, Rubio-del-Campo, Antonio, Ruiz-Partida, Rafael, Hernández-Sierra, María del Pilar, Villamayor-Belinchón, Laura, Bravo, Jerónimo, Llacer, José-Luis, Marina, Alberto, Rubio, Vicente, San-Félix, Ana, Geller, Ron, Pérez-Pérez, María-Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424185/
https://www.ncbi.nlm.nih.gov/pubmed/37471688
http://dx.doi.org/10.1021/acs.jmedchem.3c00576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424185/
https://www.ncbi.nlm.nih.gov/pubmed/37471688
http://dx.doi.org/10.1021/acs.jmedchem.3c00576

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