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A case of pulmonary tumor embolism syndrome with thrombus in transit
The incidence of pulmonary tumor embolism in patients with solid tumors is estimated to be between 3% and 26% yet is rarely diagnosed. In this case, a 74-year-old male with sarcomatoid variant of urothelial carcinoma and recently diagnosed left renal vein thrombus treated with low-molecular-weight-h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424200/ https://www.ncbi.nlm.nih.gov/pubmed/37583563 http://dx.doi.org/10.1016/j.rmcr.2023.101896 |
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author | Fuher, Alexandra de Boer, Esther Hountras, Peter |
author_facet | Fuher, Alexandra de Boer, Esther Hountras, Peter |
author_sort | Fuher, Alexandra |
collection | PubMed |
description | The incidence of pulmonary tumor embolism in patients with solid tumors is estimated to be between 3% and 26% yet is rarely diagnosed. In this case, a 74-year-old male with sarcomatoid variant of urothelial carcinoma and recently diagnosed left renal vein thrombus treated with low-molecular-weight-heparin, presented to the emergency department with acute syncope and dyspnea. He was found to have CT imaging of segmental and subsegmental arterial filling defects, a right atrial filling defect concerning for thrombus in transit and was diagnosed with pulmonary tumor embolism syndrome. The patient was treated with aspiration thrombectomy, with pathology demonstrating sarcomatoid urothelial carcinoma cells. He was initiated on a combination of gemcitabine plus carboplatin to decrease the tumor burden. While pulmonary tumor embolism syndrome is associated with a poor prognosis, prompt diagnosis and initiation of cancer-specific therapies can significantly improve survival. |
format | Online Article Text |
id | pubmed-10424200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104242002023-08-15 A case of pulmonary tumor embolism syndrome with thrombus in transit Fuher, Alexandra de Boer, Esther Hountras, Peter Respir Med Case Rep Case Report The incidence of pulmonary tumor embolism in patients with solid tumors is estimated to be between 3% and 26% yet is rarely diagnosed. In this case, a 74-year-old male with sarcomatoid variant of urothelial carcinoma and recently diagnosed left renal vein thrombus treated with low-molecular-weight-heparin, presented to the emergency department with acute syncope and dyspnea. He was found to have CT imaging of segmental and subsegmental arterial filling defects, a right atrial filling defect concerning for thrombus in transit and was diagnosed with pulmonary tumor embolism syndrome. The patient was treated with aspiration thrombectomy, with pathology demonstrating sarcomatoid urothelial carcinoma cells. He was initiated on a combination of gemcitabine plus carboplatin to decrease the tumor burden. While pulmonary tumor embolism syndrome is associated with a poor prognosis, prompt diagnosis and initiation of cancer-specific therapies can significantly improve survival. Elsevier 2023-07-20 /pmc/articles/PMC10424200/ /pubmed/37583563 http://dx.doi.org/10.1016/j.rmcr.2023.101896 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Fuher, Alexandra de Boer, Esther Hountras, Peter A case of pulmonary tumor embolism syndrome with thrombus in transit |
title | A case of pulmonary tumor embolism syndrome with thrombus in transit |
title_full | A case of pulmonary tumor embolism syndrome with thrombus in transit |
title_fullStr | A case of pulmonary tumor embolism syndrome with thrombus in transit |
title_full_unstemmed | A case of pulmonary tumor embolism syndrome with thrombus in transit |
title_short | A case of pulmonary tumor embolism syndrome with thrombus in transit |
title_sort | case of pulmonary tumor embolism syndrome with thrombus in transit |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424200/ https://www.ncbi.nlm.nih.gov/pubmed/37583563 http://dx.doi.org/10.1016/j.rmcr.2023.101896 |
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