Cargando…
Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis
Rufomycins constitute a class of cyclic heptapeptides isolated from actinomycetes. They are secondary metabolites that show promising treatment against Mycobacterium tuberculosis infections by inhibiting a novel drug target. Several nonproteinogenic amino acids are integrated into rufomycins, includ...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424215/ https://www.ncbi.nlm.nih.gov/pubmed/37451485 http://dx.doi.org/10.1016/j.jbc.2023.105049 |