APE1 promotes radiation resistance against radiation-induced pyroptosis by inhibiting the STING pathway in lung adenocarcinoma

Mammalian apurinic/apyrimidinic endonuclease 1 (APE1, APEX1) is a multifunctional enzyme that maintains cellular homeostasis. It is involved in the base excision repair (BER) pathway and plays a key role in radiation-induced DNA damage response. However, the relationship between APE1-driven radiatio...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Wei, Zixin, Yang, Chuan, Jia, Dexin, Pan, Bo, Zeng, Yuan, Sun, Di, Yu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424251/
https://www.ncbi.nlm.nih.gov/pubmed/37544034
http://dx.doi.org/10.1016/j.tranon.2023.101749

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