Cargando…
Results of resection of forearm soft tissue sarcoma
PURPOSE: Soft tissue sarcomas (STS) of the forearm are rare. We aim to assess their oncological and functional outcomes. METHODS: We retrospectively evaluated 34 patients who underwent surgical excision for forearm STS at our institution between 1993 and 2020. We analyzed postoperative Musculoskelet...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424346/ https://www.ncbi.nlm.nih.gov/pubmed/37580775 http://dx.doi.org/10.1186/s13018-023-04088-7 |
_version_ | 1785089651121324032 |
---|---|
author | Nakata, Eiji Fujiwara, Tomohiro Kunisada, Toshiyuki Nakahara, Ryuichi Katayama, Haruyoshi Itano, Takuto Ozaki, Toshifumi |
author_facet | Nakata, Eiji Fujiwara, Tomohiro Kunisada, Toshiyuki Nakahara, Ryuichi Katayama, Haruyoshi Itano, Takuto Ozaki, Toshifumi |
author_sort | Nakata, Eiji |
collection | PubMed |
description | PURPOSE: Soft tissue sarcomas (STS) of the forearm are rare. We aim to assess their oncological and functional outcomes. METHODS: We retrospectively evaluated 34 patients who underwent surgical excision for forearm STS at our institution between 1993 and 2020. We analyzed postoperative Musculoskeletal Tumor Society rating scale (MSTS) and local recurrence-free survival (LRFS), metastasis-free survival, and overall survival (OS) rates. The significance of the following variables was determined: age, sex, histology, tumor size, Fédération Nationale des Centres de Lutte contre le Cancer grade, American Joint Committee on Cancer stage, surgical margin, unplanned excision, metastases upon initial presentation, receipt of chemotherapy, and radiotherapy (RT). RESULTS: The postoperative median MSTS score was 28. Bone resection or major nerve palsy was the only factor that influenced MSTS scores. The median MSTS scores in patients with or without bone resection or major nerve palsy were 24 and 29, respectively (P < 0.001). The 5-year LRFS rates was 87%. Univariate analysis revealed that the histological diagnosis of myxofibrosarcoma was the only factor that influenced LRFS (P = 0.047). The 5-year MFS rates was 71%. In univariate analysis, no factors were associated with MFS. The 5-year OS rates was 79%. Age was the only factor that influenced OS (P = 0.01). CONCLUSION: In the treatment of forearm STS, reconstruction of the skin and tendon can compensate for function, while bone resection and major nerve disturbance cannot. Careful follow-up is important, especially in patients with myxofibrosarcoma, due to its likelihood of local recurrence. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13018-023-04088-7. |
format | Online Article Text |
id | pubmed-10424346 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104243462023-08-15 Results of resection of forearm soft tissue sarcoma Nakata, Eiji Fujiwara, Tomohiro Kunisada, Toshiyuki Nakahara, Ryuichi Katayama, Haruyoshi Itano, Takuto Ozaki, Toshifumi J Orthop Surg Res Research Article PURPOSE: Soft tissue sarcomas (STS) of the forearm are rare. We aim to assess their oncological and functional outcomes. METHODS: We retrospectively evaluated 34 patients who underwent surgical excision for forearm STS at our institution between 1993 and 2020. We analyzed postoperative Musculoskeletal Tumor Society rating scale (MSTS) and local recurrence-free survival (LRFS), metastasis-free survival, and overall survival (OS) rates. The significance of the following variables was determined: age, sex, histology, tumor size, Fédération Nationale des Centres de Lutte contre le Cancer grade, American Joint Committee on Cancer stage, surgical margin, unplanned excision, metastases upon initial presentation, receipt of chemotherapy, and radiotherapy (RT). RESULTS: The postoperative median MSTS score was 28. Bone resection or major nerve palsy was the only factor that influenced MSTS scores. The median MSTS scores in patients with or without bone resection or major nerve palsy were 24 and 29, respectively (P < 0.001). The 5-year LRFS rates was 87%. Univariate analysis revealed that the histological diagnosis of myxofibrosarcoma was the only factor that influenced LRFS (P = 0.047). The 5-year MFS rates was 71%. In univariate analysis, no factors were associated with MFS. The 5-year OS rates was 79%. Age was the only factor that influenced OS (P = 0.01). CONCLUSION: In the treatment of forearm STS, reconstruction of the skin and tendon can compensate for function, while bone resection and major nerve disturbance cannot. Careful follow-up is important, especially in patients with myxofibrosarcoma, due to its likelihood of local recurrence. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13018-023-04088-7. BioMed Central 2023-08-14 /pmc/articles/PMC10424346/ /pubmed/37580775 http://dx.doi.org/10.1186/s13018-023-04088-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Nakata, Eiji Fujiwara, Tomohiro Kunisada, Toshiyuki Nakahara, Ryuichi Katayama, Haruyoshi Itano, Takuto Ozaki, Toshifumi Results of resection of forearm soft tissue sarcoma |
title | Results of resection of forearm soft tissue sarcoma |
title_full | Results of resection of forearm soft tissue sarcoma |
title_fullStr | Results of resection of forearm soft tissue sarcoma |
title_full_unstemmed | Results of resection of forearm soft tissue sarcoma |
title_short | Results of resection of forearm soft tissue sarcoma |
title_sort | results of resection of forearm soft tissue sarcoma |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424346/ https://www.ncbi.nlm.nih.gov/pubmed/37580775 http://dx.doi.org/10.1186/s13018-023-04088-7 |
work_keys_str_mv | AT nakataeiji resultsofresectionofforearmsofttissuesarcoma AT fujiwaratomohiro resultsofresectionofforearmsofttissuesarcoma AT kunisadatoshiyuki resultsofresectionofforearmsofttissuesarcoma AT nakahararyuichi resultsofresectionofforearmsofttissuesarcoma AT katayamaharuyoshi resultsofresectionofforearmsofttissuesarcoma AT itanotakuto resultsofresectionofforearmsofttissuesarcoma AT ozakitoshifumi resultsofresectionofforearmsofttissuesarcoma |