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The mitochondrial protein TSPO in Alzheimer’s disease: relation to the severity of AD pathology and the neuroinflammatory environment
The 18kD translocator protein (TSPO) is used as a positron emission tomography (PET) target to quantify neuroinflammation in patients. In Alzheimer’s disease (AD), the cerebellum is the pseudo-reference region for comparison with the cerebral cortex due to the absence of AD pathology and lower level...
Autores principales: | Garland, Emma F., Dennett, Oliver, Lau, Laurie C., Chatelet, David S., Bottlaender, Michel, Nicoll, James A. R., Boche, Delphine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424356/ https://www.ncbi.nlm.nih.gov/pubmed/37580767 http://dx.doi.org/10.1186/s12974-023-02869-9 |
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