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Causal relationship between PCSK9 inhibitor and autoimmune diseases: a drug target Mendelian randomization study

BACKGROUND: In addition to decreasing the level of cholesterol, proprotein convertase subtilis kexin 9 (PCSK9) inhibitor has pleiotropic effects, including immune regulation. However, the impact of PCSK9 on autoimmune diseases is controversial. Therefore, we used drug target Mendelian randomization...

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Detalles Bibliográficos
Autores principales: Xie, Weijia, Li, Jiaxin, Du, Hao, Xia, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424393/
https://www.ncbi.nlm.nih.gov/pubmed/37580807
http://dx.doi.org/10.1186/s13075-023-03122-7