The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase

BACKGROUND: KH-type splicing regulatory protein (KHSRP, also called KSRP), a versatile RNA-binding protein, plays a critical role in various physiological and pathological conditions through modulating gene expressions at multiple levels. However, the role of KSRP in clear cell renal cell carcinoma...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Chieh, Lin, Yung-Wei, Lee, Wei-Jiunn, Lai, Feng-Ru, Ho, Kuo-Hao, Chu, Chih-Ying, Hua, Kuo-Tai, Chen, Ji-Qing, Tung, Min-Che, Hsiao, Michael, Wen, Yu-Ching, Chien, Ming-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424398/
https://www.ncbi.nlm.nih.gov/pubmed/37580757
http://dx.doi.org/10.1186/s12929-023-00949-9

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